The Mouse CD11a Monoclonal Antibody (PE Conjugated) - FD441/8 (AGEL0155) offered by AssayGenie is a valuable tool for researchers studying immune responses and cell adhesion processes. This monoclonal antibody specifically targets the CD11a protein, which is a key integrin involved in leukocyte adhesion and activation.By utilizing this antibody, researchers can accurately detect and analyze CD11a expression in various cell types using flow cytometry techniques. The PE conjugation enhances the versatility of this antibody, allowing for easy integration into multicolor flow cytometry experiments for comprehensive immune cell profiling.The CD11a integrin plays a crucial role in inflammatory responses and immune cell trafficking, making it a prominent target for investigations into immune disorders, inflammation, and autoimmune diseases.
By studying the expression and function of CD11a, researchers can gain insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets.In summary, the Mouse CD11a Monoclonal Antibody (PE Conjugated) - FD441/8 (AGEL0155) from AssayGenie is a reliable tool for probing CD11a expression in research settings focused on immunology, inflammation, and immune cell behavior. Its high specificity and conjugation with PE make it a valuable asset for flow cytometry-based studies seeking to unravel the intricacies of immune responses and cell adhesion processes.
Product Title:
PE Anti-Mouse CD11a Antibody [FD441.8]
SKU:
AGEL0155
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
FD441.8
Synonyms:
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).