Biotin Anti-Mouse CD119 Antibody [GR-20] (AGEL0434)

(No reviews yet) Write a Review
SKU:
AGEL0434
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a
Clone:
GR-20
Conjugation:
Biotin
Applications:
FC
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Biotin Anti-Mouse CD119 Antibody [GR-20]

The Mouse CD119 Monoclonal Antibody (Biotin Conjugated) GR-20 (AGEL0434) is a cutting-edge tool designed for researchers conducting investigations into CD119, a vital cell surface receptor involved in immune response regulation, particularly in the context of inflammation and allergic reactions. This monoclonal antibody, developed for use in mouse samples, exhibits high specificity and sensitivity, making it an excellent choice for various immunoassays and experimental techniques.Known for its ability to bind specifically to the CD119 protein, this antibody facilitates the precise detection and analysis of CD119 expression in diverse cell types, presenting an invaluable resource for studies in immunology, inflammation, and related fields. The conjugation of biotin to the antibody further enhances its utility in techniques like immunohistochemistry, flow cytometry, and more, allowing for versatile applications and detailed insights into the role of CD119 in immune system function.

CD119, also referred to as an immune receptor, plays a crucial role in modulating immune responses, with implications for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By elucidating the mechanisms by which CD119 influences immune regulation, researchers can potentially identify novel therapeutic targets and strategies for managing these complex conditions. Harnessing the potential of CD119 as a key player in immune regulation holds promise for advancing both basic research and clinical interventions in various pathologies.

Product Title:Biotin Anti-Mouse CD119 Antibody [GR-20]
SKU:AGEL0434
Size:25µg, 100µg
Clone No:GR-20
Synonyms:Interferon gamma receptor 1;Ifngr1;IFN-gamma-R1;IFN-gamma-R-alpha;CD119;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Biotin Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P15261
Gene ID:15979
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

0 Reviews

View AllClose

Related Products