GenieFluor 647 Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL1180)

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SKU:
AGEL1180
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M/K-2.7
Conjugation:
AF 647
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD106 Antibody [M/K-2.7]

The Mouse CD106 Monoclonal Antibody (AF647 Conjugated) (M/K-2.7) is a cutting-edge tool for researchers studying CD106, a key cell surface adhesion molecule involved in inflammatory responses and immune cell interactions. This antibody, conjugated with AF647 for fluorescence detection, is derived from hybridoma cells and is highly specific to mouse samples, providing reliable results in flow cytometry and immunofluorescence applications. CD106, also known as vascular cell adhesion molecule-1 (VCAM-1), plays a crucial role in the recruitment of immune cells to sites of inflammation and is implicated in various pathological conditions such as autoimmune diseases, atherosclerosis, and cancer metastasis.

By targeting CD106, researchers can gain insights into the mechanisms behind these diseases and develop potential therapeutic interventions to modulate immune responses.The Mouse CD106 Monoclonal Antibody (AF647 Conjugated) (M/K-2.7) offers a powerful tool for investigating the function of CD106 in immunology, vascular biology, and disease pathology. Its high specificity and fluorescence detection capabilities make it an essential reagent for studies aiming to elucidate the role of CD106 in immune cell adhesion and inflammation regulation.

Product Title:GenieFluor 647 Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:AGEL1180
Size:25µg, 100µg
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:Genie Fluor 647 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P29533
Gene ID:22329
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).

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