GenieFluor 488 Anti-Mouse CD106 Antibody [M/K-2.7] (AGEL1179)

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SKU:
AGEL1179
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M/K-2.7
Conjugation:
AF 488
Frequently bought together:

Description

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GenieFluor 488 Anti-Mouse CD106 Antibody [M/K-2.7]

The Mouse CD106 Monoclonal Antibody (AF488 Conjugated) (M/K-2.7) is a specialized tool for researchers studying CD106, a cell surface protein involved in immune responses and inflammation regulation. This high-quality monoclonal antibody, conjugated with AF488 for convenient fluorescent detection, is derived from mouse sources and validated for exceptional performance in various applications.CD106, also known as vascular cell adhesion molecule-1 (VCAM-1), plays a pivotal role in mediating leukocyte adhesion and transmigration during the inflammatory response. This antibody specifically targets CD106, enabling researchers to detect and analyze its expression in a wide range of cell types.

Its usage is particularly valuable in immunology research and investigations related to inflammatory conditions, atherosclerosis, and other diseases where CD106 expression is implicated.By utilizing the Mouse CD106 Monoclonal Antibody (AF488 Conjugated) (M/K-2.7), researchers can gain valuable insights into the role of CD106 in immune cell interactions and inflammatory processes. This antibody is a critical tool for advancing our understanding of immune regulation mechanisms and developing potential therapeutic interventions targeting CD106 in various disease settings.

Product Title:GenieFluor 488 Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:AGEL1179
Size:25µg, 100µg
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:Genie Fluor 488 Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P29533
Gene ID:22329
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).

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