Cathepsin H (CTSH), which can act both as an aminopeptidase and as an endopeptidase, is a lysosomal cysteine protease of the papain family. CTSH is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. CTSH is associated with various pathological conditions like human fibrous meningioma, colorectal cancer, arthritis, human prostate tumor and lung cancer. CTSH is associated with cancer progression because of their ability to degrade extracellular matrices facilitating invasion, angiogenesis and metastasis as is evident from numerous clinical reports and experimental models. The expression of CTSH is significantly increased in disease states such as in prostate tumors, sera of asthmatic patients, and mucosa of colorectal cancer patients.
Product Name:
Mouse Cathepsin H/CTSH Recombinant Protein (RPES5112)
Recombinant Mouse Cathepsin H is produced by our Mammalian expression system and the target gene encoding Glu22-Val333 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
36.1 kDa
AP Mol Mass:
36-40 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_alt데이터시트Mouse Cathepsin B/CTSB Recombinant Protein Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of pr
system_update_alt데이터시트Human Cathepsin B/CTSB Recombinant Protein Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of pr
system_update_alt데이터시트Human Cathepsin S/CTSS Recombinant Protein Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially
