MLLT3 Antibody (PACO44394)
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주문- SKU:
- PACO44394
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MLLT3 Antibody (PACO44394) |
Antibody SKU: | PACO44394 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein AF-9 protein (1-150AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO44394 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO44394 at dilution of 1:100. |
Background: | Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. |
Synonyms: | Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3), MLLT3, AF9 YEATS3 |
UniProt Protein Function: | MLLT3: A chromosomal aberration involving MLLT3 is associated with acute leukemias. Translocation t(9;11)(p22;q23) with MLL/HRX. The result is a rogue activator protein. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Oncoprotein Chromosomal Location of Human Ortholog: 9p22 Cellular Component: transcription elongation factor complex; nucleus Molecular Function:protein binding Biological Process: anterior/posterior pattern formation; segment specification; regulation of transcription, DNA-dependent; transcription, DNA-dependent |
UniProt Code: | P42568 |
NCBI GenInfo Identifier: | 215273971 |
NCBI Gene ID: | 4300 |
NCBI Accession: | P42568.2 |
UniProt Secondary Accession: | P42568,Q8IVB0, B1AMQ2, B2R7B3, B7Z755, D3DRJ8, |
UniProt Related Accession: | P42568 |
Molecular Weight: | 568 |
NCBI Full Name: | Protein AF-9 |
NCBI Synonym Full Names: | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 |
NCBI Official Symbol: | MLLT3 |
NCBI Official Synonym Symbols: | AF9; YEATS3 |
NCBI Protein Information: | protein AF-9; YEATS domain-containing protein 3; ALL1-fused gene from chromosome 9 protein; myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 3 |
UniProt Protein Name: | Protein AF-9 |
UniProt Synonym Protein Names: | ALL1-fused gene from chromosome 9 protein; Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein; YEATS domain-containing protein 3 |
UniProt Gene Name: | MLLT3 |
UniProt Entry Name: | AF9_HUMAN |