MIOS Antibody (PACO63207)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO63207
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MIOS Antibody (PACO63207) |
Antibody SKU: | PACO63207 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human GATOR complex protein MIOS protein (1-237AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO63207 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | As a component of the GATOR subcomplex GATOR2, functions within the amino acid, sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid, sensors SESN2 and CASTOR1. |
Synonyms: | GATOR complex protein MIOS (Missing oocyte meiosis regulator homolog), MIOS |
UniProt Protein Function: | MIOS: Belongs to the WD repeat mio family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 7p21.3 Cellular Component: nucleoplasm; lysosomal membrane; cytoplasm; cell junction; nucleus |
UniProt Code: | Q9NXC5 |
NCBI GenInfo Identifier: | 109150419 |
NCBI Gene ID: | 54468 |
NCBI Accession: | NP_061878.3 |
UniProt Secondary Accession: | Q9NXC5,O75216, Q7L551, Q9H092, B2RTV6, |
UniProt Related Accession: | Q9NXC5 |
Molecular Weight: | 64,016 Da |
NCBI Full Name: | WD repeat-containing protein mio |
NCBI Synonym Full Names: | missing oocyte, meiosis regulator, homolog (Drosophila) |
NCBI Official Symbol: | MIOS |
NCBI Protein Information: | WD repeat-containing protein mio |
UniProt Protein Name: | WD repeat-containing protein mio |
Protein Family: | WD repeat-containing protein |
UniProt Gene Name: | MIOS |
UniProt Entry Name: | MIO_HUMAN |
Antibodies |
Anti-MIOS Antibody (CAB18260) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |