MAK Antibody (PACO47522)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO47522
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MAK Antibody (PACO47522) |
Antibody SKU: | PACO47522 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Serine/threonine-protein kinase MAK protein (200-440AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Mouse brain tissue. All lanes: MAK antibody at 2.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 71, 74, 67 kDa. Observed band size: 71 kDa.. |
![]() | Immunofluorescent analysis of A549 cells using PACO47522 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO47522 at dilution of 1:100. |
Background: | Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells. |
Synonyms: | Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase), MAK |
UniProt Protein Function: | MAK: a protein kinase of the RCK family of kinases. It is expressed at high levels in the testis (primarily in germ cells), and in developing sensory epithelia. Localizes to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. |
UniProt Protein Details: | Protein type:Protein kinase, CMGC; EC 2.7.11.22; Nuclear receptor co-regulator; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CMGC group; RCK family Chromosomal Location of Human Ortholog: 6p24 Cellular Component: centrosome; midbody; nucleus; photoreceptor inner segment; photoreceptor outer segment Molecular Function:protein binding; transcription coactivator activity Biological Process: photoreceptor cell maintenance; protein amino acid autophosphorylation; protein amino acid phosphorylation Disease: Retinitis Pigmentosa 62 |
NCBI Summary: | The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
UniProt Code: | P20794 |
NCBI GenInfo Identifier: | 13432166 |
NCBI Gene ID: | 4117 |
NCBI Accession: | P20794.2 |
UniProt Secondary Accession: | P20794,Q547D0, Q9NUH7, F1T0K6, G1FL29, |
UniProt Related Accession: | P20794 |
Molecular Weight: | 66,345 Da |
NCBI Full Name: | Serine/threonine-protein kinase MAK |
NCBI Synonym Full Names: | male germ cell associated kinase |
NCBI Official Symbol: | MAK |
NCBI Official Synonym Symbols: | RP62 |
NCBI Protein Information: | serine/threonine-protein kinase MAK |
UniProt Protein Name: | Serine/threonine-protein kinase MAK |
UniProt Synonym Protein Names: | Male germ cell-associated kinase |
Protein Family: | Makatoxin |
UniProt Gene Name: | MAK |
UniProt Entry Name: | MAK_HUMAN |
Antibodies | ELISA Kits |
Anti-MAK Antibody (CAB17508) | MAK Colorimetric Cell-Based ELISA Kit |
Phospho-MAK (Y159) Antibody (PACO04276) | |
MAK Antibody (PACO04277) | |
MAK Antibody (PACO10350) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |