MAG Antibody (PACO14671)
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주문- SKU:
- PACO14671
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | MAG Antibody (PACO14671) |
Antibody SKU: | PACO14671 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human MAG |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse brain tissue, Primary antibody: PACO14671(MAG Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO14671(MAG Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. |
Synonyms: | myelin associated glycoprotein |
UniProt Protein Function: | MAG: Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3- linked sialic acid. Binds to RTN4R. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.1 Cellular Component: paranode region of axon; plasma membrane; integral to membrane Molecular Function:carbohydrate binding Biological Process: substantia nigra development; nerve growth factor receptor signaling pathway; negative regulation of axonogenesis; regulation of axonogenesis; cell adhesion; blood coagulation; leukocyte migration |
NCBI Summary: | The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010] |
UniProt Code: | P20916 |
NCBI GenInfo Identifier: | 126689 |
NCBI Gene ID: | 4099 |
NCBI Accession: | P20916.1 |
UniProt Secondary Accession: | P20916,Q567S4, B7Z2E5, F5GYC0, |
UniProt Related Accession: | P20916 |
Molecular Weight: | 66,224 Da |
NCBI Full Name: | Myelin-associated glycoprotein |
NCBI Synonym Full Names: | myelin associated glycoprotein |
NCBI Official Symbol: | MAG |
NCBI Official Synonym Symbols: | GMA; S-MAG; SIGLEC4A; SIGLEC-4A |
NCBI Protein Information: | myelin-associated glycoprotein; sialic acid binding Ig-like lectin 4A; sialic acid-binding immunoglobulin-like lectin 4A |
UniProt Protein Name: | Myelin-associated glycoprotein |
UniProt Synonym Protein Names: | Siglec-4a |
Protein Family: | Magainins |
UniProt Gene Name: | MAG |
UniProt Entry Name: | MAG_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |