LYRM1 Antibody (PACO28094)
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주문- SKU:
- PACO28094
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | LYRM1 Antibody (PACO28094) |
Antibody SKU: | PACO28094 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human LYR motif-containing protein 1 protein (1-122AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO28094 at dilution of 1:100. |
Background: | May promote cell proliferation and inhibition of apoptosis of preadipocytes. |
Synonyms: | LYR motif-containing protein 1, LYRM1 |
UniProt Protein Function: | LYRM1: May promote cell proliferation and inhibition of apoptosis of preadipocytes. When overexpressed, may be involved in obesity- associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes. Belongs to the complex I LYR family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: nucleoplasm; intercellular bridge; mitochondrion |
NCBI Summary: | The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] |
UniProt Code: | O43325 |
NCBI GenInfo Identifier: | 119587248 |
NCBI Gene ID: | 57149 |
NCBI Accession: | EAW66844 |
UniProt Related Accession: | O43325 |
Molecular Weight: | 14 kDa |
NCBI Full Name: | hypothetical protein A-211C6.1, isoform CRA_b |
NCBI Synonym Full Names: | LYR motif containing 1 |
NCBI Official Symbol: | LYRM1 |
NCBI Official Synonym Symbols: | A211C6.1 |
NCBI Protein Information: | LYR motif-containing protein 1 |
UniProt Protein Name: | LYR motif-containing protein 1 |
Protein Family: | LYR motif containing protein |
UniProt Gene Name: | LYRM1 |
UniProt Entry Name: | LYRM1_HUMAN |
Antibodies |
Anti-LYRM1 Antibody (CAB15483) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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