LTB4R2 Antibody (PACO19960)
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주문- SKU:
- PACO19960
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | LTB4R2 Antibody (PACO19960) |
Antibody SKU: | PACO19960 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:20-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human LTB4R2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO19960(LTB4R2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19960(LTB4R2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. |
Synonyms: | leukotriene B4 receptor 2 |
UniProt Protein Function: | LTB4R2: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 14q12 Cellular Component: integral to plasma membrane; membrane; plasma membrane Molecular Function:leukotriene B4 receptor activity; leukotriene receptor activity; peptide receptor activity, G-protein coupled Biological Process: chemotaxis; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inflammatory response; negative regulation of adenylate cyclase activity; neuropeptide signaling pathway |
UniProt Code: | Q9NPC1 |
NCBI GenInfo Identifier: | 23821812 |
NCBI Gene ID: | 56413 |
NCBI Accession: | Q9NPC1.1 |
UniProt Secondary Accession: | Q9NPC1,Q5KU28, Q9NPE5, |
UniProt Related Accession: | Q9NPC1 |
Molecular Weight: | 37,942 Da |
NCBI Full Name: | Leukotriene B4 receptor 2 |
NCBI Synonym Full Names: | leukotriene B4 receptor 2 |
NCBI Official Symbol: | LTB4R2 |
NCBI Official Synonym Symbols: | BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2 |
NCBI Protein Information: | leukotriene B4 receptor 2 |
UniProt Protein Name: | Leukotriene B4 receptor 2 |
UniProt Synonym Protein Names: | LTB4 receptor JULF2; Leukotriene B4 receptor BLT2; Seven transmembrane receptor BLTR2 |
Protein Family: | Leukotriene B4 receptor |
UniProt Gene Name: | LTB4R2 |
UniProt Entry Name: | LT4R2_HUMAN |
Antibodies |
Anti-LTB4R2 Antibody (CAB15479) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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