LSM4 Antibody (PACO28045)
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주문- SKU:
- PACO28045
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | LSM4 Antibody (PACO28045) |
Antibody SKU: | PACO28045 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human U6 snRNA-associated Sm-like protein LSm4 protein (1-139AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: LSM4 antibody at 2µg/ml Lane 1: A549 whole cell lysate Lane 2: K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 16 kDa Observed band size: 16 kDa . |
![]() | Immunofluorescent analysis of MCF-7 cells using PACO28045 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO28045 at dilution of 1:100. |
Background: | Binds specifically to the 3'-terminal U-tract of U6 snRNA. |
Synonyms: | U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP), LSM4 |
UniProt Protein Function: | LSM4: Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family. |
UniProt Protein Details: | Protein type:RNA-binding; Spliceosome Chromosomal Location of Human Ortholog: 19p13.11 Cellular Component: small nuclear ribonucleoprotein complex; spliceosome; cytosol Molecular Function:protein binding Biological Process: RNA splicing; gene expression; mRNA processing; mRNA catabolic process, deadenylation-dependent decay |
NCBI Summary: | This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q9Y4Z0 |
NCBI GenInfo Identifier: | 10720082 |
NCBI Gene ID: | 25804 |
NCBI Accession: | Q9Y4Z0.1 |
UniProt Related Accession: | Q9Y4Z0 |
Molecular Weight: | Calculated MW: 15kDaObserved MW: 15kDa |
NCBI Full Name: | U6 snRNA-associated Sm-like protein LSm4 |
NCBI Synonym Full Names: | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
NCBI Official Symbol: | LSM4 |
NCBI Official Synonym Symbols: | GRP; YER112W |
NCBI Protein Information: | U6 snRNA-associated Sm-like protein LSm4; glycine-rich protein |
UniProt Protein Name: | U6 snRNA-associated Sm-like protein LSm4 |
UniProt Synonym Protein Names: | Glycine-rich protein; GRP |
Protein Family: | Sm-like protein |
UniProt Gene Name: | LSM4 |
UniProt Entry Name: | LSM4_HUMAN |