KTN1 Antibody (PACO58236)
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주문- SKU:
- PACO58236
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IP
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KTN1 Antibody (PACO58236) |
Antibody SKU: | PACO58236 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IP |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500, IP:1:200-1:2000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Kinectin protein (978-1116AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: MCF-7 whole cell lysate, Jurkat whole cell lysate. All lanes: KTN1 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 157, 150, 151, 153 kDa. Observed band size: 157 kDa. |
![]() | IHC image of PACO58236 diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | IHC image of PACO58236 diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin. |
Synonyms: | Kinectin (CG-1 antigen) (Kinesin receptor), KTN1, CG1 KIAA0004 |
UniProt Protein Function: | KTN1: Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin. Parallel homodimers formed between the membrane-bound and the cytosolic form, and also between 2 cytosolic forms. High levels in peripheral blood lymphocytes, testis and ovary, lower levels in spleen, thymus, prostate, small intestine and colon. Belongs to the kinectin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 14q22.3 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; integral to plasma membrane; membrane Molecular Function:cadherin binding; kinesin binding; protein binding; RNA binding |
NCBI Summary: | This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2012] |
UniProt Code: | Q86UP2 |
NCBI GenInfo Identifier: | 34098465 |
NCBI Gene ID: | 3895 |
NCBI Accession: | Q86UP2.1 |
UniProt Secondary Accession: | Q86UP2,Q13999, Q14707, Q15387, Q17RZ5, Q5GGW3, Q86W57 B4DZ88, |
UniProt Related Accession: | Q86UP2 |
Molecular Weight: | 156kDa |
NCBI Full Name: | Kinectin |
NCBI Synonym Full Names: | kinectin 1 |
NCBI Official Symbol: | KTN1 |
NCBI Official Synonym Symbols: | CG1; KNT; MU-RMS-40.19 |
NCBI Protein Information: | kinectin |
UniProt Protein Name: | Kinectin |
UniProt Synonym Protein Names: | CG-1 antigen; Kinesin receptor |
Protein Family: | Kinectin |
UniProt Gene Name: | KTN1 |
Antibodies |
Anti-KTN1 Antibody (CAB12456) |
Anti-KTN1 Antibody (CAB14016) |
Anti-KTN1 Antibody (CAB5879) |
KTN1 Antibody (PACO10178) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |