KLK2 Antibody (PACO18125)
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주문- SKU:
- PACO18125
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KLK2 Antibody (PACO18125) |
Antibody SKU: | PACO18125 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human KLK2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18125(KLK2 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO18125(KLK2 Antibody) at dilution 1/1650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO18125(KLK2 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. |
Synonyms: | kallikrein-related peptidase 2 |
UniProt Protein Function: | KLK2: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.21.35; Protease Chromosomal Location of Human Ortholog: 19q13.41 Cellular Component: extracellular region Molecular Function:serine-type endopeptidase activity Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis |
NCBI Summary: | This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012] |
UniProt Code: | P20151 |
NCBI GenInfo Identifier: | 125174 |
NCBI Gene ID: | 3817 |
NCBI Accession: | P20151.1 |
UniProt Secondary Accession: | P20151,Q15946, Q9UJZ9, B4DU93, B4DUB0, F5H8L3, |
UniProt Related Accession: | P20151 |
Molecular Weight: | 261 |
NCBI Full Name: | Kallikrein-2 |
NCBI Synonym Full Names: | kallikrein-related peptidase 2 |
NCBI Official Symbol: | KLK2 |
NCBI Official Synonym Symbols: | hK2; hGK-1; KLK2A2 |
NCBI Protein Information: | kallikrein-2; tissue kallikrein-2; glandular kallikrein 2; glandular kallikrein-1; kallikrein 2, prostatic |
UniProt Protein Name: | Kallikrein-2 |
UniProt Synonym Protein Names: | Glandular kallikrein-1; hGK-1; Tissue kallikrein-2 |
Protein Family: | Kallikrein |
UniProt Gene Name: | KLK2 |
UniProt Entry Name: | KLK2_HUMAN |
Antibodies | ELISA Kits |
Anti-KLK2 Antibody (CAB12268) | Human KLK2 / Kallikrein 2 ELISA Kit |
Anti-KLK2 Antibody (CAB2990) | Human Kallikrein-2 (KLK2) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |