KLK10 Antibody (PACO33404)
- SKU:
- PACO33404
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KLK10 Antibody (PACO33404) |
Antibody SKU: | PACO33404 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Kallikrein-10 protein (31-274AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Has a tumor-suppressor role for NES1 in breast and prostate cancer. |
Synonyms: | Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1), KLK10, NES1 PRSSL1 |
UniProt Protein Function: | KLK10: Has a tumor-suppressor role for NES1 in breast and prostate cancer. Belongs to the peptidase S1 family. Kallikrein subfamily. |
UniProt Protein Details: | Protein type:Secreted; Tumor suppressor; Protease; Secreted, signal peptide; EC 3.4.21.- Chromosomal Location of Human Ortholog: 19q13 Molecular Function:serine-type peptidase activity |
NCBI Summary: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | O43240 |
NCBI GenInfo Identifier: | 317373432 |
NCBI Gene ID: | 5655 |
NCBI Accession: | O43240.3 |
UniProt Secondary Accession: | O43240,Q53YL3, Q99920, Q9GZW9, A6NC12, |
UniProt Related Accession: | O43240 |
Molecular Weight: | 30,170 Da |
NCBI Full Name: | Kallikrein-10 |
NCBI Synonym Full Names: | kallikrein related peptidase 10 |
NCBI Official Symbol: | KLK10 |
NCBI Official Synonym Symbols: | NES1; PRSSL1 |
NCBI Protein Information: | kallikrein-10 |
UniProt Protein Name: | Kallikrein-10 |
UniProt Synonym Protein Names: | Normal epithelial cell-specific 1; Protease serine-like 1 |
Protein Family: | Kallikrein |
UniProt Gene Name: | KLK10 |
UniProt Entry Name: | KLK10_HUMAN |