KLK1 Antibody (PACO14626)
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주문- SKU:
- PACO14626
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KLK1 Antibody (PACO14626) |
Antibody SKU: | PACO14626 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human KLK1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO14626(KLK1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO14626(KLK1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. |
Synonyms: | kallikrein 1 |
UniProt Protein Function: | KLK1: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Belongs to the peptidase S1 family. Kallikrein subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Protease; EC 3.4.21.35 Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: nucleus Molecular Function:serine-type endopeptidase activity Biological Process: proteolysis Disease: Kallikrein, Decreased Urinary Activity Of |
NCBI Summary: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008] |
UniProt Code: | P06870 |
NCBI GenInfo Identifier: | 269849612 |
NCBI Gene ID: | 3816 |
NCBI Accession: | P06870.2 |
UniProt Secondary Accession: | P06870,Q66US9, Q86U61, Q8TCV8, Q9BS53, Q9NQU4, Q9UD19 Q9UMJ1, |
UniProt Related Accession: | P06870 |
Molecular Weight: | 23,835 Da |
NCBI Full Name: | Kallikrein-1 |
NCBI Synonym Full Names: | kallikrein 1 |
NCBI Official Symbol: | KLK1 |
NCBI Official Synonym Symbols: | hK1; KLKR; Klk6 |
NCBI Protein Information: | kallikrein-1; tissue kallikrein; glandular kallikrein 1; kallikrein serine protease 1; kallikrein 1, renal/pancreas/salivary; kidney/pancreas/salivary gland kallikrein |
UniProt Protein Name: | Kallikrein-1 |
UniProt Synonym Protein Names: | Kidney/pancreas/salivary gland kallikrein; Tissue kallikrein |
Protein Family: | Kallikrein 1-related peptidase |
UniProt Gene Name: | KLK1 |
UniProt Entry Name: | KLK1_HUMAN |
Antibodies | ELISA Kits |
Anti-KLK1 Antibody (CAB1807) | Human Kallikrein-1 (KLK1) ELISA Kit |
KLK1 Antibody (PACO02125) | |
KLK1 Antibody (PACO10142) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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