KLF7 Antibody (PACO14617)
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주문- SKU:
- PACO14617
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KLF7 Antibody (PACO14617) |
Antibody SKU: | PACO14617 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human KLF7 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO14617(KLF7 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Humna colon cancer tissue, mouse kidney tissue, mouse testis tissue, human fetal brain tissue, Primary antibody: PACO14617(KLF7 Antibody) at dilution 1/483.3, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO14617(KLF7 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. |
Synonyms: | Kruppel-like factor 7 (ubiquitous) |
UniProt Protein Function: | KLF7: Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. Belongs to the krueppel C2H2-type zinc-finger protein family. |
UniProt Protein Details: | Protein type:DNA-binding; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 2q32 Cellular Component: nucleus Molecular Function:DNA binding; zinc ion binding; transcription coactivator activity; transcription factor activity Biological Process: regulation of transcription from RNA polymerase II promoter; axon guidance; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; dendrite morphogenesis |
NCBI Summary: | The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
UniProt Code: | O75840 |
NCBI GenInfo Identifier: | 401709918 |
NCBI Gene ID: | 8609 |
NCBI Accession: | NP_001257871.1 |
UniProt Secondary Accession: | O75840,Q7Z3H8, Q96E51, B2RB03, B7Z4F7, C9JF04, E7EWH1 L0R4P2, |
UniProt Related Accession: | O75840 |
Molecular Weight: | 33kd |
NCBI Full Name: | Krueppel-like factor 7 isoform 2 |
NCBI Synonym Full Names: | Kruppel-like factor 7 (ubiquitous) |
NCBI Official Symbol: | KLF7 |
NCBI Official Synonym Symbols: | UKLF |
NCBI Protein Information: | Krueppel-like factor 7 |
UniProt Protein Name: | Krueppel-like factor 7 |
UniProt Synonym Protein Names: | Ubiquitous krueppel-like factor |
Protein Family: | Krueppel-like factor |
UniProt Gene Name: | KLF7 |
UniProt Entry Name: | KLF7_HUMAN |
Antibodies | ELISA Kits |
Anti-KLF7 Antibody (CAB8879) | KLF7 Transcription Factor Activity Assay |
KLF7 Antibody (PACO05586) | |
KLF7 Antibody (PACO10127) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |