KIFC3 Antibody (PACO45602)
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주문- SKU:
- PACO45602
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | KIFC3 Antibody (PACO45602) |
Antibody SKU: | PACO45602 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Kinesin-like protein KIFC3 protein (140-390AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO45602 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO45602 at dilution of 1:100. |
Background: | Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance. |
Synonyms: | Kinesin-like protein KIFC3, KIFC3 |
UniProt Protein Function: | KIFC3: Minus-end microtubule-dependent motor protein. Involved in apically targeted transport. Required for zonula adherens maintenance. Belongs to the kinesin-like protein family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Motor; Microtubule-binding Chromosomal Location of Human Ortholog: 16q13-q21 Cellular Component: Golgi apparatus; microtubule; kinesin complex; centrosome; cytoplasmic vesicle membrane; zonula adherens Molecular Function:microtubule binding; ATPase activity; microtubule motor activity; ATP binding Biological Process: visual perception; metabolic process; zonula adherens maintenance; Golgi organization and biogenesis; microtubule-based movement |
NCBI Summary: | KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 [PubMed 9782090]).[supplied by OMIM, Mar 2009] |
UniProt Code: | Q9BVG8 |
NCBI GenInfo Identifier: | 194294508 |
NCBI Gene ID: | 3801 |
NCBI Accession: | NP_001123571.1 |
UniProt Secondary Accession: | Q9BVG8,O75299, Q49A29, Q49AQ0, Q59G19, Q8IUT3, Q96HW6 A8K6S2, B7Z484, |
UniProt Related Accession: | Q9BVG8 |
Molecular Weight: | 94,276 Da |
NCBI Full Name: | kinesin-like protein KIFC3 isoform 3 |
NCBI Synonym Full Names: | kinesin family member C3 |
NCBI Official Symbol: | KIFC3 |
NCBI Protein Information: | kinesin-like protein KIFC3 |
UniProt Protein Name: | Kinesin-like protein KIFC3 |
Protein Family: | Kinesin-like protein |
UniProt Gene Name: | KIFC3 |
UniProt Entry Name: | KIFC3_HUMAN |