ITPKB Antibody (PACO44772)
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주문- SKU:
- PACO44772
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ITPKB Antibody (PACO44772) |
Antibody SKU: | PACO44772 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Inositol-trisphosphate 3-kinase B protein (1-260AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | cytosol, inositol-1,4,5-trisphosphate 3-kinase activity, cellular response to calcium ion, inositol phosphate metabolic process, inositol trisphosphate metabolic process, signal transduction |
Synonyms: | Inositol-trisphosphate 3-kinase B (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase B) (IP3 3-kinase B) (IP3K B) (InsP 3-kinase B), ITPKB |
UniProt Protein Function: | ITPKB: The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:EC 2.7.1.127; Motility/polarity/chemotaxis; Carbohydrate Metabolism - inositol phosphate; Kinase, lipid Chromosomal Location of Human Ortholog: 1q42.13 Cellular Component: cytosol Molecular Function:calmodulin binding; protein binding; inositol trisphosphate 3-kinase activity; ATP binding Biological Process: cell surface receptor linked signal transduction; inositol phosphate metabolic process; MAPKKK cascade; positive regulation of Ras protein signal transduction; signal transduction; positive regulation of alpha-beta T cell differentiation; positive thymic T cell selection |
NCBI Summary: | The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008] |
UniProt Code: | P27987 |
NCBI GenInfo Identifier: | 62906885 |
NCBI Gene ID: | 3707 |
NCBI Accession: | P27987.5 |
UniProt Secondary Accession: | P27987,Q5VWL9, Q5VWM0, Q96BZ2, Q96JS1, Q9UH47, |
UniProt Related Accession: | P27987 |
Molecular Weight: | 946 |
NCBI Full Name: | Inositol-trisphosphate 3-kinase B |
NCBI Synonym Full Names: | inositol-trisphosphate 3-kinase B |
NCBI Official Symbol: | ITPKB |
NCBI Official Synonym Symbols: | IP3K; IP3KB; PIG37; IP3K-B; IP3-3KB |
NCBI Protein Information: | inositol-trisphosphate 3-kinase B; IP3K B; IP3 3-kinase B; insP 3-kinase B; proliferation-inducing protein 37; inositol 1,4,5-trisphosphate 3-kinase B |
UniProt Protein Name: | Inositol-trisphosphate 3-kinase B |
UniProt Synonym Protein Names: | Inositol 1,4,5-trisphosphate 3-kinase B; IP3 3-kinase B; IP3K B; InsP 3-kinase B |
Protein Family: | Inositol-trisphosphate 3-kinase |
UniProt Gene Name: | ITPKB |
UniProt Entry Name: | IP3KB_HUMAN |