ITGA3 Antibody (PACO06587)
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주문- SKU:
- PACO06587
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ITGA3 Antibody (PACO06587) |
Antibody SKU: | PACO06587 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from the Internal region of human Integrin α 3. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot analysis of 293 HepG2 RAT-STOMACH cells using Integrin alpha 3 Polyclonal Antibody. | |
Western Blot analysis of HepG2 cells using Integrin alpha 3 Polyclonal Antibody. |
Synonyms: | ITGA3; MSK18; Integrin α-3; CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit α; CD antigen CD49c |
UniProt Protein Function: | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
NCBI Summary: | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015] |
UniProt Code: | P26006 |
NCBI GenInfo Identifier: | 347595830 |
NCBI Gene ID: | 3675 |
NCBI Accession: | P26006.5 |
UniProt Secondary Accession: | P26006,A7E246, B7ZM80, B9EGQ1, D3DTX4, D3DTX5, |
UniProt Related Accession: | P26006 |
Molecular Weight: | |
NCBI Full Name: | Integrin alpha-3 |
NCBI Synonym Full Names: | integrin subunit alpha 3 |
NCBI Official Symbol: | ITGA3 |
NCBI Official Synonym Symbols: | VL3A; CD49C; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3 |
NCBI Protein Information: | integrin alpha-3 |
UniProt Protein Name: | Integrin alpha-3 |
UniProt Synonym Protein Names: | CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3 |
Protein Family: | Integrin |
UniProt Gene Name: | ITGA3 |
UniProt Entry Name: | ITA3_HUMAN |