INPP5J Antibody (PACO44265)
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주문- SKU:
- PACO44265
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | INPP5J Antibody (PACO44265) |
Antibody SKU: | PACO44265 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A protein (60-360AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO44265 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO44265 at dilution of 1:100. |
Background: | Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles (By similarity). |
Synonyms: | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase J), INPP5J, PIB5PA PIPP |
UniProt Protein Function: | PI5PA: Inositol 5-phosphatase, which converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4- phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate- binding proteins that are present at membranes ruffles. Belongs to the inositol 1,4,5-trisphosphate 5- phosphatase type II family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - inositol phosphate; EC 3.1.3.56; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 22q12.2 Cellular Component: ruffle; growth cone; cytoplasm; plasma membrane; dendritic shaft; cytosol Molecular Function:inositol-polyphosphate 5-phosphatase activity; SH3 domain binding Biological Process: inositol phosphate metabolic process; negative regulation of microtubule polymerization; phospholipid metabolic process; phosphatidylinositol biosynthetic process; negative regulation of peptidyl-serine phosphorylation; phosphoinositide dephosphorylation |
UniProt Code: | Q15735 |
NCBI GenInfo Identifier: | 116242713 |
NCBI Gene ID: | 27124 |
NCBI Accession: | Q15735.3 |
UniProt Secondary Accession: | Q15735,Q32M61, Q6ZTH6, Q8N902, Q9UDT9, B3KS54, |
UniProt Related Accession: | Q15735 |
Molecular Weight: | 1006 |
NCBI Full Name: | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A |
NCBI Synonym Full Names: | inositol polyphosphate-5-phosphatase J |
NCBI Official Symbol: | INPP5J |
NCBI Official Synonym Symbols: | PIPP; INPP5; PIB5PA |
NCBI Protein Information: | phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; inositol polyphosphate 5-phosphatase J; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A |
UniProt Protein Name: | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A |
UniProt Synonym Protein Names: | Inositol polyphosphate 5-phosphatase J |
Protein Family: | Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
UniProt Gene Name: | INPP5J |
UniProt Entry Name: | PI5PA_HUMAN |