UniProt Protein Function: | INPP4: inositol polyphosphate 4-phosphatase type I, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. |
UniProt Protein Details: | Protein type:Phosphatase, lipid; EC 3.1.3.66; Carbohydrate Metabolism - inositol phosphate Chromosomal Location of Human Ortholog: 2q11.2 Cellular Component: cytosol Molecular Function:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity Biological Process: inositol phosphate metabolic process; dephosphorylation; phospholipid metabolic process; phosphatidylinositol biosynthetic process; signal transduction |
NCBI Summary: | This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2008] |
UniProt Code: | Q96PE3 |
NCBI GenInfo Identifier: | 119622315 |
NCBI Gene ID: | 3631 |
NCBI Accession: | EAX01910.1 |
UniProt Secondary Accession: | Q96PE3,O15326, Q13187, Q53TD8, Q8TC02, |
UniProt Related Accession: | Q96PE3 |
Molecular Weight: | 109,956 Da |
NCBI Full Name: | inositol polyphosphate-4-phosphatase, type I, 107kDa, isoform CRA_f |
NCBI Synonym Full Names: | inositol polyphosphate-4-phosphatase, type I, 107kDa |
NCBI Official Symbol: | INPP4A |
NCBI Official Synonym Symbols: | INPP4; TVAS1 |
NCBI Protein Information: | type I inositol 3,4-bisphosphate 4-phosphatase; type I inositol-3,4-bisphosphate 4-phosphatase; inositol polyphosphate-4-phosphatase, type I, 107kD |
UniProt Protein Name: | Type I inositol 3,4-bisphosphate 4-phosphatase |
UniProt Synonym Protein Names: | Inositol polyphosphate 4-phosphatase type I |
Protein Family: | Type I inositol 3,4-bisphosphate 4-phosphatase |
UniProt Gene Name: | INPP4A |
UniProt Entry Name: | INP4A_HUMAN |