IL31 Antibody (PACO19830)
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주문- SKU:
- PACO19830
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IL31 Antibody (PACO19830) |
Antibody SKU: | PACO19830 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human IL31 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19830(IL31 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: PACO19830(IL31 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19830(IL31 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. |
Synonyms: | interleukin 31 |
UniProt Protein Function: | IL31: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity. |
UniProt Protein Details: | Protein type:Secreted; Cytokine; Secreted, signal peptide Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: extracellular space Molecular Function:cytokine activity Biological Process: immune system process |
NCBI Summary: | IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q6EBC2 |
NCBI GenInfo Identifier: | 62122911 |
NCBI Gene ID: | 386653 |
NCBI Accession: | NP_001014358.1 |
UniProt Secondary Accession: | Q6EBC2,A2RUQ1, |
UniProt Related Accession: | Q6EBC2 |
Molecular Weight: | 18,205 Da |
NCBI Full Name: | interleukin-31 |
NCBI Synonym Full Names: | interleukin 31 |
NCBI Official Symbol: | IL31 |
NCBI Official Synonym Symbols: | IL-31 |
NCBI Protein Information: | interleukin-31 |
UniProt Protein Name: | Interleukin-31 |
Protein Family: | Interleukin |
UniProt Gene Name: | IL31 |
UniProt Entry Name: | IL31_HUMAN |
Antibodies | ELISA Kits |
Anti-IL-31 Antibody (CAB14982) | Human Interleukin-31 (IL-31) ELISA Kit |
IL31 Antibody (PACO07313) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |