IL18 Antibody (PACO13574)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO13574
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | IL18 Antibody (PACO13574) |
Antibody SKU: | PACO13574 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Human Pre-IL18 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | interleukin 18 (interferon-gamma-inducing factor);IL18;IGIF;IL-18;IL-1g;IL1F4;MGC12320 ; |
UniProt Protein Function: | IL18: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Belongs to the IL-1 family. |
UniProt Protein Details: | Protein type:Cytokine Chromosomal Location of Human Ortholog: 11q22.2-q22.3 Cellular Component: extracellular space; extracellular region; cytosol Molecular Function:protein binding; cytokine activity Biological Process: positive regulation of granulocyte macrophage colony-stimulating factor production; positive regulation of NK T cell proliferation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; positive regulation of activated T cell proliferation; chemokine biosynthetic process; cell-cell signaling; lipopolysaccharide-mediated signaling pathway; granulocyte macrophage colony-stimulating factor biosynthetic process; angiogenesis; inflammatory response; positive regulation of interleukin-17 production; regulation of cell adhesion; positive regulation of natural killer cell proliferation; T-helper 1 type immune response; T-helper 2 type immune response; interleukin-2 biosynthetic process; MAPKKK cascade; interleukin-13 biosynthetic process; sleep; positive regulation of tissue remodeling; positive regulation of interferon-gamma production; interferon-gamma biosynthetic process; immune response; negative regulation of myoblast differentiation; positive regulation of inflammatory response |
NCBI Summary: | The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011] |
UniProt Code: | Q14116 |
NCBI GenInfo Identifier: | 3219817 |
NCBI Gene ID: | 3606 |
NCBI Accession: | Q14116.1 |
UniProt Secondary Accession: | Q14116,O75599, Q6FGY3, Q6WWJ7, |
UniProt Related Accession: | Q14116 |
Molecular Weight: | 21,896 Da |
NCBI Full Name: | Interleukin-18 |
NCBI Synonym Full Names: | interleukin 18 |
NCBI Official Symbol: | IL18 |
NCBI Official Synonym Symbols: | IGIF; IL-18; IL-1g; IL1F4 |
NCBI Protein Information: | interleukin-18; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor) |
UniProt Protein Name: | Interleukin-18 |
UniProt Synonym Protein Names: | Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma |
Protein Family: | Interleukin |
UniProt Gene Name: | IL18 |
UniProt Entry Name: | IL18_HUMAN |