IGHMBP2 Antibody (PACO47482)
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주문- SKU:
- PACO47482
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IGHMBP2 Antibody (PACO47482) |
Antibody SKU: | PACO47482 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human DNA-binding protein SMUBP-2 protein (646-884AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO47482 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human brain tissue using PACO47482 at dilution of 1:100. |
Background: | 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation (By similarity). DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV. |
Synonyms: | DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Glial factor 1) (GF-1) (Immunoglobulin mu-binding protein 2), IGHMBP2, SMBP2 SMUBP2 |
UniProt Protein Function: | 5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV. |
NCBI Summary: | This gene encodes a helicase superfamily member that binds a specific DNA sequence from the immunoglobulin mu chain switch region. Mutations in this gene lead to spinal muscle atrophy with respiratory distress type 1. [provided by RefSeq, Jul 2008] |
UniProt Code: | P38935 |
NCBI GenInfo Identifier: | 119392094 |
NCBI Gene ID: | 3508 |
NCBI Accession: | NP_002171.2 |
UniProt Secondary Accession: | P38935,Q00443, Q14177, A0PJD2, |
UniProt Related Accession: | P38935 |
Molecular Weight: | 109 |
NCBI Full Name: | DNA-binding protein SMUBP-2 |
NCBI Synonym Full Names: | immunoglobulin mu binding protein 2 |
NCBI Official Symbol: | IGHMBP2 |
NCBI Official Synonym Symbols: | HCSA; HMN6; CATF1; CMT2S; SMARD1; SMUBP2; ZFAND7 |
NCBI Protein Information: | DNA-binding protein SMUBP-2 |
UniProt Protein Name: | DNA-binding protein SMUBP-2 |
UniProt Synonym Protein Names: | ATP-dependent helicase IGHMBP2; Glial factor 1; GF-1; Immunoglobulin mu-binding protein 2 |
UniProt Gene Name: | IGHMBP2 |
Antibodies |
Anti-IGHMBP2 Antibody (CAB16053) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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