IFT57 Antibody (PACO09888)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO09888
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | IFT57 Antibody (PACO09888) |
Antibody SKU: | PACO09888 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human IFT57 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | intraflagellar transport 57 homolog (Chlamydomonas);IFT57;ESRRBL1;FLJ10147;HIPPI;MHS4R2 ; |
UniProt Protein Function: | IFT57: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. Belongs to the IFT57 family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q13.13 Cellular Component: Golgi apparatus; centrosome; photoreceptor connecting cilium; cilium Molecular Function:protein binding; DNA binding Biological Process: regulation of apoptosis; caspase activation; smoothened signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis; organelle organization and biogenesis; neural tube closure; intraflagellar transport; cilium biogenesis; heart looping; negative regulation of epithelial cell proliferation |
UniProt Code: | Q9NWB7 |
NCBI GenInfo Identifier: | 74734638 |
NCBI Gene ID: | 55081 |
NCBI Accession: | Q9NWB7.1 |
UniProt Secondary Accession: | Q9NWB7,Q96DA9, |
UniProt Related Accession: | Q9NWB7 |
Molecular Weight: | 429 |
NCBI Full Name: | Intraflagellar transport protein 57 homolog |
NCBI Synonym Full Names: | intraflagellar transport 57 |
NCBI Official Symbol: | IFT57 |
NCBI Official Synonym Symbols: | HIPPI; MHS4R2; ESRRBL1 |
NCBI Protein Information: | intraflagellar transport protein 57 homolog; HIP1 protein interactor; HIP1-interacting protein; dermal papilla-derived protein 8; intraflagellar transport 57 homolog; estrogen-related receptor beta like 1; estrogen-related receptor beta-like protein 1; huntingtin interacting protein-1 interacting protein |
UniProt Protein Name: | Intraflagellar transport protein 57 homolog |
UniProt Synonym Protein Names: | Dermal papilla-derived protein 8; Estrogen-related receptor beta-like protein 1; HIP1-interacting protein; MHS4R2 |
Protein Family: | Intraflagellar transport protein |
UniProt Gene Name: | IFT57 |
UniProt Entry Name: | IFT57_HUMAN |