ICAM5 Antibody (PACO19805)
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주문- SKU:
- PACO19805
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ICAM5 Antibody (PACO19805) |
Antibody SKU: | PACO19805 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human ICAM5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19805(ICAM5 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19805(ICAM5 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. |
Synonyms: | intercellular adhesion molecule 5, telencephalin |
UniProt Protein Function: | ICAM5: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). Belongs to the immunoglobulin superfamily. ICAM family. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:integrin binding; protein binding Biological Process: cell-cell adhesion; cell adhesion; phagocytosis |
NCBI Summary: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UMF0 |
NCBI GenInfo Identifier: | 296439327 |
NCBI Gene ID: | 7087 |
NCBI Accession: | Q9UMF0.3 |
UniProt Related Accession: | Q9UMF0 |
Molecular Weight: | 97kDa |
NCBI Full Name: | Intercellular adhesion molecule 5 |
NCBI Synonym Full Names: | intercellular adhesion molecule 5 |
NCBI Official Symbol: | ICAM5 |
NCBI Official Synonym Symbols: | TLN; TLCN |
NCBI Protein Information: | intercellular adhesion molecule 5 |
UniProt Protein Name: | Intercellular adhesion molecule 5 |
UniProt Synonym Protein Names: | Telencephalin |
Protein Family: | Intercellular adhesion molecule |
UniProt Gene Name: | ICAM5 |
UniProt Entry Name: | ICAM5_HUMAN |