V-Set and Immunoglobulin Domain-Containing Protein 2 (VSIG2) is presumably a 50-60 kDa single-pass type I transmembrane (glyco)protein which contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in the stomach; colon; prostate; trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families; including immunoglobulin light and heavy chains; in several T-cell receptors such as CD2 (Cluster of Differentiation 2); CD4; CD80; and CD86; in myelin membrane adhesion molecules; in junction adhesion molecules (JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). It shows expression in stomach and prostate by Northern blot; and likely participates in cell adhesion. Human VSIG2 precursor is 327 amino acids in length.
Product Name:
Human VSIG2 Recombinant Protein (RPES2756)
Product Code:
RPES2756
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
V-Set and Immunoglobulin Domain-Containing Protein 2, Cortical Thymocyte-Like Protein, CT-Like Protein, VSIG2, CTH, CTXL
Accession:
Q96IQ7-1
Sequence:
Val24-Ala243
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human V-Set and Immunoglobulin Domain-Containing Protein 2 is produced by our Mammalian expression system and the target gene encoding Val24-Ala243 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
24.2 kDa
AP Mol Mass:
30-33 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
