Human Vaspin/SerpinA12 Recombinant Protein (RPES5075)

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SKU:
RPES5075
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human Vaspin/SerpinA12 Recombinant Protein

Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets; nine ?-helices; and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity; insulin resistance; and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.

Product Name:Human Vaspin/SerpinA12 Recombinant Protein (RPES5075)
Product Code:RPES5075
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Serpin A12, OL-64, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, Visceral Adipose-Specific Serpin, SERPINA12
Accession:Q8IW75
Sequence:Leu21-Lys414
Fusion tag:N-GST
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Serpin A12 is produced by our E.coli expression system and the target gene encoding Leu21-Lys414 is expressed with a GST tag at the N-terminus.
Purity:> 90% as determined by reducing SDS-PAGE.
Mol Mass:71.4 kDa
AP Mol Mass:72 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 50mM TrisHCl; 160mM NaCl; 0.2mM PMSF; 1mM DTT; 10% Glycerine; pH 7.2 .
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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