Human USE1 Recombinant Protein (RPPB5092)

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SKU:
RPPB5092
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
USE1
Synonyms:
Vesicle transport protein USE1
Synonyms:
Putative MAPK-activatingprotein PM26
Synonyms:
USE1-like protein
Synonyms:
p31
Source:
Escherichia Coli
Uniprot:
Q9NZ43
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Description

Product Name:Human USE1 Recombinant Protein
Product Code:RPPB5092
Size:10µg
Species:Human
Target:USE1
Synonyms:Vesicle transport protein USE1, Putative MAPK-activatingprotein PM26, USE1-like protein, p31, USE1L, MDS032, Q-SNARE, SLT1, SNARE-LikeTail-Anchored Protein 1 Homolog, Protein P31.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:USE1 protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH8.0), 10% glycerol, 0.1M NaCl and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 80.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAASRLE LNLVRLLSRC EAMAAEKRDP DEWRLEKYVG ALEDMLQALKVHASKPASEV INEYSWKVDF LKGMLQAEKL TSSSEKALAN QFLAPGRVPT TARERVPATK TVHLQSRARYTSEMRSELLG TDSAEPEMDV RKRTGVAGSQ PVSEKQSAAE LDLVLQRHQN LQEKLAEEML GLARSLKTNT LAAQSVIKKD NQTLSHSLKMADQNLEKLKT ESERLEQHTQ KSVN

USE1Belongs to the USE1 family, this protein is a vesicle transport protein. USE1is a component of a SNAREcomplex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. In additionUSE1 interacts directly with STX18. SNAREmay be involvedin targeting and fusion of Golgi-derived retrograde transport vesicles with theER. Diseases associated with USE1 comprise dysentery and hemolytic-uremicsyndrome. Among its related super-pathways are Nicotine Pathway (DopaminergicNeuron) and Pharmacodynamics. GO annotations related to this gene includeprotein binding.

USE1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 254 amino acids (1-231 a.a) and having a molecular mass of 28.3kDa.USE1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:USE1L: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Belongs to the USE1 family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; lysosome

Molecular Function:protein binding

Biological Process: ER to Golgi vesicle-mediated transport; lysosomal transport; protein catabolic process; retrograde vesicle-mediated transport, Golgi to ER; secretion by cell

UniProt Code:Q9NZ43
NCBI GenInfo Identifier:296452858
NCBI Gene ID:55850
NCBI Accession:Q9NZ43.2
UniProt Secondary Accession:Q9NZ43,Q8NCK1, Q9BRT4,
UniProt Related Accession:Q9NZ43
Molecular Weight:15,063 Da
NCBI Full Name:Vesicle transport protein USE1
NCBI Synonym Full Names:unconventional SNARE in the ER 1
NCBI Official Symbol:USE1  
NCBI Official Synonym Symbols:D12; P31; SLT1; MDS032  
NCBI Protein Information:vesicle transport protein USE1
UniProt Protein Name:Vesicle transport protein USE1
UniProt Synonym Protein Names:Putative MAPK-activating protein PM26; USE1-like protein; p31
Protein Family:Protein transport protein
UniProt Gene Name:USE1  
UniProt Entry Name:USE1_HUMAN
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