Human TXNL4B Recombinant Protein (RPPB5055)

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SKU:
RPPB5055
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
TXNL4B
Synonyms:
Thioredoxin-like protein 4B
Synonyms:
Dim1-like protein
Synonyms:
TXNL4B
Synonyms:
DIM2
Source:
Escherichia Coli
Uniprot:
Q9NX01
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Description

Product Name:Human TXNL4B Recombinant Protein
Product Code:RPPB5055
Size:10µg
Species:Human
Target:TXNL4B
Synonyms:Thioredoxin-like protein 4B, Dim1-like protein, TXNL4B, DIM2, DLP.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:TXNL4B protein solution (0. 5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 100mM NaCl.
Stability:TXNL4B Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSFL LPKLTSKKEV DQAIKSTAEK VLVLRFGRDE DPVCLQLDDI LSKTSSDLSK MAAIYLVDVD QTAVYTQYFD ISYIPSTVFF FNGQHMKVDY GSPDHTKFVG SFKTKQDFID LIEVIYRGAM RGKLIVQSPI DPKNIPKYDL LYQDI

TXNL4B is a member of the DIM1 family which has a vital role in pro-mRNA splicing. TXNL4B is required in cell cycle progression for S/G2 transition and interacts with PRPF6 subunit of the spliceosome.

TXNL4B produced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids (1-149 a.a) and having a molecular mass of 21.1kDa.TXNL4B is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:TXNL4B: Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition. Belongs to the DIM1 family.
UniProt Protein Details:

Protein type:RNA-binding

Chromosomal Location of Human Ortholog: 16q22.2

Cellular Component: spliceosome; U4/U6 x U5 tri-snRNP complex; snRNP U5

Biological Process: mitosis; spliceosome assembly

UniProt Code:Q9NX01
NCBI GenInfo Identifier:51702156
NCBI Gene ID:54957
NCBI Accession:Q9NX01.1
UniProt Secondary Accession:Q9NX01,D3DWS6,
UniProt Related Accession:Q9NX01
Molecular Weight:149
NCBI Full Name:Thioredoxin-like protein 4B
NCBI Synonym Full Names:thioredoxin-like 4B
NCBI Official Symbol:TXNL4B  
NCBI Official Synonym Symbols:DLP; Dim2  
NCBI Protein Information:thioredoxin-like protein 4B; Dim1-like protein
UniProt Protein Name:Thioredoxin-like protein 4B
UniProt Synonym Protein Names:Dim1-like protein
Protein Family:Thioredoxin-like protein
UniProt Gene Name:TXNL4B  
UniProt Entry Name:TXN4B_HUMAN
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