Human TPRKB Recombinant Protein (RPPB4995)

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SKU:
RPPB4995
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
TPRKB
Synonyms:
TP53RK binding protein
Synonyms:
PRPK-binding protein
Synonyms:
PRPK (p53-related protein kinase)-binding protein
Synonyms:
CGI-121
Source:
Escherichia Coli
Uniprot:
Q9Y3C4
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Description

Product Name:Human TPRKB Recombinant Protein
Product Code:RPPB4995
Size:10µg
Species:Human
Target:TPRKB
Synonyms:TP53RK binding protein, PRPK-binding protein, PRPK (p53-related protein kinase)-binding protein, CGI-121.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The TPRKB solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 150mM NaCl and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMQLTHQ LDLFPECRVT LLLFKDVKNA GDLRRKAMEG TIDGSLINPT VIVDPFQILV AANKAVHLYK LGKMKTRTLS TEIIFNLSPN NNISEALKKF GISANDTSIL IVYIEEGEKQ INQEYLISQV EGHQVSLKNL PEIMNITEVK KIYKLSSQEE SIGTLLDAII CRMSTKDVL

TPRKB is a member of the CGI121/TPRKB family. TPRKB is localized to nucleus and cytoplasm and is ubiquitously expressed. TPRKB is known to cooperate with TP53RK/PRPK.

TPRKB Human Recombinant produced E. coli is a single polypeptide chain containing 199 amino acids (1-175) and having a molecular mass of 22.2kDa.TPRKB is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:TPRKB: Belongs to the CGI121/TPRKB family. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 2p24.3-p24.1Cellular Component: cytoplasm; cytosol; nucleusMolecular Function: protein binding; protein kinase bindingBiological Process: tRNA processing
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9Y3C4
NCBI GenInfo Identifier:7705590
NCBI Gene ID:51002
NCBI Accession:NP_057142.1
UniProt Secondary Accession:Q9Y3C4,Q8IWR6, Q8IWR7, Q9H3K4, D6W5H6
UniProt Related Accession:Q9Y3C4
Molecular Weight:19,661 Da
NCBI Full Name:EKC/KEOPS complex subunit TPRKB
NCBI Synonym Full Names:TP53RK binding protein
NCBI Official Symbol:TPRKB  
NCBI Official Synonym Symbols:CGI-121  
NCBI Protein Information:EKC/KEOPS complex subunit TPRKB; PRPK-binding protein; TP53RK-binding protein; PRPK (p53-related protein kinase)-binding protein
UniProt Protein Name:EKC/KEOPS complex subunit TPRKB
UniProt Synonym Protein Names:PRPK-binding protein; TP53RK-binding protein
Protein Family:EKC/KEOPS complex
UniProt Gene Name:TPRKB  
UniProt Entry Name:TPRKB_HUMAN
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