Human TACO1 Recombinant Protein (RPPB4896)

(No reviews yet) Write a Review

제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.

주문
SKU:
RPPB4896
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
TACO1
Synonyms:
Translational Activator Of Mitochondrially Encoded Cytochrome C Oxidase
Synonyms:
CCDC44
Synonyms:
Coiled-Coil Domain-Containing Protein 44
Synonyms:
Coiled-Coil Domain Containing 44
Source:
Escherichia Coli
Uniprot:
Q9BSH4
€0.00
Frequently bought together:

Description

Product Name:Human TACO1 Recombinant Protein
Product Code:RPPB4896
Size:20µg
Species:Human
Target:TACO1
Synonyms:Translational Activator Of Mitochondrially Encoded Cytochrome C Oxidase, CCDC44, Coiled-Coil Domain-Containing Protein 44, Coiled-Coil Domain Containing 44, Clone HQ0477 PRO0477p, Translational Activator Of Cytochrome C Oxidase 1, Translational Activator Of Mitochondrially-Encoded Cytochrome C Oxidase I.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:TACO1 protein solution (0.5mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSNKWSKVR HIKGPKDVER SRIFSKLCLN IRLAVKEGGP NPEHNSNLAN ILEVCRSKHM PKSTIETALK MEKSKDTYLL YEGRGPGGSS LLIEALSNSS HKCQADIRHI LNKNGGVMAV GARHSFDKKG VIVVEVEDRE KKAVNLERAL EMAIEAGAEDVKETEDEEER NVFKFICDAS SLHQVRKKLD SLGLCSVSCA LEFIPNSKVQ LAEPDLEQAA HLIQALSNHE DVIHVYDNIE

Translationalactivator of mitochondrially encoded cytochrome c oxidase I (TACO1) belongs tothe TACO1 family. TACO1 is a mitochondrial protein which functions as atranslational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutationsin this gene are associated with Leigh syndrome.

TACO1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 260 amino acids (61-297 a.a) and having a molecular mass of 28.8kDa.TACO1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:CCDC44: Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1. Defects in TACO1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency. Belongs to the TACO1 family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: mitochondrion; nucleus

Disease: Mitochondrial Complex Iv Deficiency

NCBI Summary:This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]
UniProt Code:Q9BSH4
NCBI GenInfo Identifier:33516968
NCBI Gene ID:51204
NCBI Accession:Q9BSH4.1
UniProt Secondary Accession:Q9BSH4,Q8N3N6, Q9UI60, B2RD21,
UniProt Related Accession:Q9BSH4
Molecular Weight:32,477 Da
NCBI Full Name:Translational activator of cytochrome c oxidase 1
NCBI Synonym Full Names:translational activator of cytochrome c oxidase I
NCBI Official Symbol:TACO1  
NCBI Official Synonym Symbols:CCDC44  
NCBI Protein Information:translational activator of cytochrome c oxidase 1
UniProt Protein Name:Translational activator of cytochrome c oxidase 1
UniProt Synonym Protein Names:Coiled-coil domain-containing protein 44; Translational activator of mitochondrially-encoded cytochrome c oxidase I
Protein Family:Translational activator of cytochrome c oxidase
UniProt Gene Name:TACO1  
UniProt Entry Name:TACO1_HUMAN
View AllClose

Related Products