Human STAT3 Recombinant Protein (RPES5009)

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SKU:
RPES5009
Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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Description

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Human STAT3 Recombinant Protein

Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

Product Name:Human STAT3 Recombinant Protein (RPES5009)
Product Code:RPES5009
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Signal Transducer and Activator of Transcription 3, Acute-Phase Response Factor, STAT3, APRF
Accession:P40763
Sequence:Met 1-Asn175
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Signal Transducer and Activator of Transcription 3 is produced by our E.coli expression system and the target gene encoding Met1-Asn175 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:21.8 kDa
AP Mol Mass:18 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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