Human SDSL Recombinant Protein (RPPB2265)

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SKU:
RPPB2265
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
SDSL
Synonyms:
Serine dehydratase-like
Synonyms:
SDS-RS1
Synonyms:
Serine dehydratase 2
Synonyms:
TDH
Source:
Escherichia Coli
Uniprot:
Q96GA7
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Description

Product Name:Human SDSL Recombinant Protein
Product Code:RPPB2265
Size:10µg
Species:Human
Target:SDSL
Synonyms:Serine dehydratase-like, SDS-RS1, Serine dehydratase 2, TDH, L-serine dehydratase/L-threonine deaminase, SDH 2, serine dehydratase related sequence 1, EC 4.3.1.17, EC 4.3.1.19.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The SDSL solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.1M NaCl and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMDGPVA EHAKQEPFHV VTPLLESWAL SQVAGMPVFL KCENVQPSGS FKIRGIGHFC QEMAKKGCRH LVCSSGGNAG IAAAYAARKL GIPATIVLPE STSLQVVQRL QGEGAEVQLT GKVWDEANLR AQELAKRDGW ENVPPFDHPL IWKGHASLVQ ELKAVLRTPP GALVLAVGGG GLLAGVVAGL LEVGWQHVPI IAMETHGAHC FNAAITAGKL VTLPDITSVA KSLGAKTVAA RALECMQVCK IHSEVVEDTE AVSAVQQLLD DERMLVEPAC GAALAAIYSG LLRRLQAEGC LPPSLTSVVV IVCGGNNINS RELQALKTHL GQV

SDSL belongs to the serine/threonine dehydratase family and function as a serinespecific dehydratase. SDSL utilizes pyridoxal phosphate and is one of three key enzymes which take part in the metabolism of Glycine and serine.

SDSL Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 353 amino acids (1-329) and having a molecular mass of 37.3 kDa.SDSL is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:SDSL: Has low serine dehydratase and threonine dehydratase activity. Belongs to the serine/threonine dehydratase family.
UniProt Protein Details:

Protein type:EC 4.3.1.17; EC 4.3.1.19; Lyase

Chromosomal Location of Human Ortholog: 12q24.13

Cellular Component: cytoplasm

Molecular Function:pyridoxal phosphate binding

UniProt Code:Q96GA7
NCBI GenInfo Identifier:74731799
NCBI Gene ID:113675
NCBI Accession:Q96GA7.1
UniProt Related Accession:Q96GA7
Molecular Weight:34,674 Da
NCBI Full Name:Serine dehydratase-like
NCBI Synonym Full Names:serine dehydratase like
NCBI Official Symbol:SDSL  
NCBI Official Synonym Symbols:TDH; cSDH; SDH 2; SDS-RS1  
NCBI Protein Information:serine dehydratase-like
UniProt Protein Name:Serine dehydratase-like
UniProt Synonym Protein Names:L-serine deaminase; L-serine dehydratase/L-threonine deaminase; L-threonine dehydratase (EC:4.3.1.19); TDH; Serine dehydratase 2 (EC:4.3.1.17); SDH 2
Protein Family:Serine dehydratase
UniProt Gene Name:SDSL  
UniProt Entry Name:SDSL_HUMAN
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