S100A13 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. It is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. It plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. It binds two calcium ions per subunit and one copper ion. Binding of one copper ion does not interfere with calcium binding. It is required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine.
Product Name:
Human S100A13 Recombinant Protein (RPES3209)
Product Code:
RPES3209
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Protein S100-A13,S100A13,S100 calcium-binding protein A13
Accession:
NP_001019381.1
Sequence:
Ala2-Lys98
Fusion tag:
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Protein S100-A13 is produced by our E.coli expression system and the target gene encoding Ala2-Lys98 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
11.3 kDa
AP Mol Mass:
29 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB?150mM NaCl,pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
