Human RPE Recombinant Protein (RPPB2255)
- SKU:
- RPPB2255
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- RPE
- Synonyms:
- Ribulose-phosphate 3-epimerase
- Ribulose-5-phosphate-3-epimerase
- RPE
- HUSSY-17
- Source:
- Escherichia Coli
- Uniprot:
- Q96AT9
Description
| Product Name: | Human RPE Recombinant Protein |
| Product Code: | RPPB2255 |
| Size: | 20µg |
| Species: | Human |
| Target: | RPE |
| Synonyms: | Ribulose-phosphate 3-epimerase, Ribulose-5-phosphate-3-epimerase, RPE, HUSSY-17, RPE2-1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The RPE solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 30% glycerol and 200mM NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMASGCK IGPSILNSDL ANLGAECLRM LDSGADYLHL DVMDGHFVPN ITFGHPVVES LRKQLGQDPF FDMHMMVSKP EQWVKPMAVA GANQYTFHLE ATENPGALIK DIRENGMKVG LAIKPGTSVE YLAPWANQID MALVMTVEPG FGGQKFMEDM MPKVHWLRTQ FPSLDIEVDG GVGPDTVHKC AEAGANMIVS GSAIMRSEDP RSVINLLRNV CSEAAQKRSL DR |
Ribulose-phosphate 3-epimerase (RPE) is a member of the ribulose-phosphate 3-epimerase family. RPE is the enzyme which converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. Therefore, the RPE enzyme has one substrate, D-ribulose 5-phosphate, and one product, D-xylulose 5-phosphate. RPE participates in three metabolic pathways: pentose phosphate pathway, pentose and glucuronate interconversions, and carbon fixation.
RPE Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 252 amino acids (1-228) and having a molecular mass of 27.5kDa.RPE is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | RPE: Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate. Belongs to the ribulose-phosphate 3-epimerase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Isomerase; Carbohydrate Metabolism - pentose and glucuronate interconversions; EC 5.1.3.1; Carbohydrate Metabolism - pentose phosphate pathway Chromosomal Location of Human Ortholog: 2q32-q33.3 Cellular Component: cytosol Molecular Function:identical protein binding; protein homodimerization activity; ribulose-phosphate 3-epimerase activity; metal ion binding Biological Process: pentose-phosphate shunt; carbohydrate metabolic process; pentose-phosphate shunt, non-oxidative branch; pentose catabolic process; pathogenesis; cellular carbohydrate metabolic process |
| UniProt Code: | Q96AT9 |
| NCBI GenInfo Identifier: | 506949360 |
| NCBI Gene ID: | 6120 |
| NCBI Accession: | NP_001265211.1 |
| UniProt Secondary Accession: | Q96AT9,Q8VEE0, |
| UniProt Related Accession: | Q96AT9 |
| Molecular Weight: | 17,570 Da |
| NCBI Full Name: | ribulose-phosphate 3-epimerase isoform 2 |
| NCBI Synonym Full Names: | ribulose-5-phosphate-3-epimerase |
| NCBI Official Symbol: | RPE |
| NCBI Official Synonym Symbols: | RPE2-1 |
| NCBI Protein Information: | ribulose-phosphate 3-epimerase |
| UniProt Protein Name: | Ribulose-phosphate 3-epimerase |
| UniProt Synonym Protein Names: | Ribulose-5-phosphate-3-epimerase |
| Protein Family: | Ribulose-phosphate 3-epimerase |
| UniProt Gene Name: | RPE |
| UniProt Entry Name: | RPE_HUMAN |
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