Human RAB2B Recombinant Protein (RPPB4358)

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SKU:
RPPB4358
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
RAB2B
Synonyms:
Ras-related protein Rab-2B
Synonyms:
RAB2B
Source:
Escherichia Coli
Uniprot:
Q8WUD1
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Description

Product Name:Human RAB2B Recombinant Protein
Product Code:RPPB4358
Size:20µg
Species:Human
Target:RAB2B
Synonyms:Ras-related protein Rab-2B, RAB2B.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:RAB2B protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1mM DTT and 0.15M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMTYAYL FKYIIIGDTG VGKSCLLLQF TDKRFQPVHD LTIGVEFGAR MVNIDGKQIK LQIWDTAGQE SFRSITRSYY RGAAGALLVY DITRRETFNH LTSWLEDARQ HSSSNMVIML IGNKSDLESR RDVKREEGEA FAREHGLIFM ETSAKTACNV EEAFINTAKE IYRKIQQGLF DVHNEANGIK IGPQQSISTS VGPSASQRNS RDIGSNSGCC

Rab2B is a member of the small GTPase superfamily, whose members are nontransforming monomeric GTP-binding proteins of the Ras superfamily and contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins engaged in vesicular fusion and trafficking.

RAB2B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 240 amino acids (1-216 a.a.) and having a molecular mass of 26.8kDa. RAB2B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:RAB2B: Required for protein transport from the endoplasmic reticulum to the Golgi complex (Potential). Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric; G protein; G protein, monomeric, RabChromosomal Location of Human Ortholog: 14q11.2Molecular Function: protein bindingBiological Process: positive regulation of exocytosis
UniProt Protein Details:
NCBI Summary:Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]
UniProt Code:Q8WUD1
NCBI GenInfo Identifier:28436385
NCBI Gene ID:84932
NCBI Accession:Q8WUD1.1
UniProt Secondary Accession:Q8WUD1,Q6NZ33, B2RD03, D3DS24
UniProt Related Accession:Q8WUD1
Molecular Weight:16,667 Da
NCBI Full Name:Ras-related protein Rab-2B
NCBI Synonym Full Names:RAB2B, member RAS oncogene family
NCBI Official Symbol:RAB2B  
NCBI Official Synonym Symbols:
NCBI Protein Information:ras-related protein Rab-2B
UniProt Protein Name:Ras-related protein Rab-2B
UniProt Synonym Protein Names:
Protein Family:Ras-related protein
UniProt Gene Name:RAB2B  
UniProt Entry Name:RAB2B_HUMAN
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