Human PSMG3 Recombinant Protein (RPPB4327)

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SKU:
RPPB4327
Product type:
Recombinant Protein
Size:
5ug
Species:
Human
Target:
PSMG3
Synonyms:
Proteasome assembly chaperone 3
Synonyms:
PAC-3
Synonyms:
hPAC3
Synonyms:
PSMG3
Source:
Escherichia Coli
Uniprot:
Q9BT73
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Description

Product Name:Human PSMG3 Recombinant Protein
Product Code:RPPB4327
Size:5µg
Species:Human
Target:PSMG3
Synonyms:Proteasome assembly chaperone 3, PAC-3, hPAC3, PSMG3, PAC3, C7orf48, MGC10911.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The PSMG3 solution (0.5 mg/ml) contains 20mM Tris-HCl Buffer (pH 8.0) and 10% Glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MEDTPLVISK QKTEVVCGVP TQVVCTAFSS HILVVVTQFG KMGTLVSLEP SSVASDVSKP VLTTKVLLGQ DEPLIHVFAK NLVAFVSQEA GNRAVLLAVA VKDKSMEGLK ALREVIRVCQ VW

PSMG3 is a chaperone protein that promotes assembly of the 20S proteasome. PSMG3 may cooperate with PSMG1-PSMG2 heterodimers to coordinate the correct assembly of proteasomes. PSMG3 interacts with PSMG4, as well as directly with alpha and beta subunits of the 20S proteasome but dissociates prior to the formation of half-proteasomes, probably upon recruitment of POMP.

PSMG3 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 142 amino acids (1-122 a.a.) and having a molecular mass of 15.2kDa. The PSMG3 is purified by proprietary chromatographic techniques.

UniProt Protein Function:PSMG3: Chaperone protein which promotes assembly of the 20S proteasome. May cooperate with PSMG1-PSMG2 heterodimers to orchestrate the correct assembly of proteasomes. Belongs to the PSMG3 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 7p22.3
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9BT73
NCBI GenInfo Identifier:197245458
NCBI Gene ID:84262
NCBI Accession:NP_001127812.1
UniProt Secondary Accession:Q9BT73,A4D216, A8MPW2
UniProt Related Accession:Q9BT73
Molecular Weight:13,104 Da
NCBI Full Name:proteasome assembly chaperone 3
NCBI Synonym Full Names:proteasome (prosome, macropain) assembly chaperone 3
NCBI Official Symbol:PSMG3  
NCBI Official Synonym Symbols:PAC3; C7orf48  
NCBI Protein Information:proteasome assembly chaperone 3; PAC-3; hPAC3; proteasome assembling chaperone 3
UniProt Protein Name:Proteasome assembly chaperone 3
UniProt Synonym Protein Names:
Protein Family:
UniProt Gene Name:PSMG3  
UniProt Entry Name:PSMG3_HUMAN
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