Human PRTFDC1 Recombinant Protein (RPPB2194)
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주문- SKU:
- RPPB2194
- Product type:
- Recombinant Protein
- Size:
- 20ug
- Species:
- Human
- Target:
- PRTFDC1
- Synonyms:
- Phosphoribosyltransferase domain-containing protein 1
- Synonyms:
- PRTFDC1
- Synonyms:
- HHGP
- Source:
- Escherichia Coli
- Uniprot:
- Q9NRG1
Description
| Product Name: | Human PRTFDC1 Recombinant Protein |
| Product Code: | RPPB2194 |
| Size: | 20µg |
| Species: | Human |
| Target: | PRTFDC1 |
| Synonyms: | Phosphoribosyltransferase domain-containing protein 1, PRTFDC1, HHGP. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | PRTFDC1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | PRTFDC1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAGSSEE APDYGRGVVI MDDWPGYDLN LFTYPQHYYG DLEYVLIPHG IIVDRIERLA KDIMKDIGYS DIMVLCVLKG GYKFCADLVE HLKNISRNSD RFVSMKVDFI RLKSYRNDQS MGEMQIIGGD DLSTLAGKNV LIVEDVVGTG RTMKALLSNI EKYKPNMIKV ASLLVKRTSR SDGFRPDYAG FEIPNLFVVG YALDYNEYFR DLNHICVINE HGKEKYRV |
Phosphoribosyltransferase domain-containing protein 1 (PRTFDC1) is a member of the purine/pyrimidine phosphoribosyltransferase family. PRTFDC1 has a low, barely measurable phosphoribosyltransferase activity (in vitro). PRTFDC1 can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). PRTFDC1 is not expected to impact purine metabolism or GMP salvage.
PRTFDC1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 248 amino acids (1-225 a.a.) and having a molecular mass of 28.1kDa.PRTFDC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PRTFDC1: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage. Belongs to the purine/pyrimidine phosphoribosyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 10p12.1 Cellular Component: cytosol Molecular Function:hypoxanthine phosphoribosyltransferase activity; magnesium ion binding; protein binding; protein homodimerization activity Biological Process: adenine salvage; GMP catabolic process; GMP salvage; guanine salvage; hypoxanthine metabolic process; IMP salvage |
| UniProt Code: | Q9NRG1 |
| NCBI GenInfo Identifier: | 74752920 |
| NCBI Gene ID: | 56952 |
| NCBI Accession: | Q9NRG1.1 |
| UniProt Secondary Accession: | Q9NRG1,Q53HA7, Q59EL9, Q5VV18, Q5VV20, B7Z1Z3, |
| UniProt Related Accession: | Q9NRG1 |
| Molecular Weight: | 19,983 Da |
| NCBI Full Name: | Phosphoribosyltransferase domain-containing protein 1 |
| NCBI Synonym Full Names: | phosphoribosyl transferase domain containing 1 |
| NCBI Official Symbol: | PRTFDC1 |
| NCBI Official Synonym Symbols: | HHGP |
| NCBI Protein Information: | phosphoribosyltransferase domain-containing protein 1 |
| UniProt Protein Name: | Phosphoribosyltransferase domain-containing protein 1 |
| Protein Family: | Phosphoribosyltransferase domain-containing protein |
| UniProt Gene Name: | PRTFDC1 |
| UniProt Entry Name: | PRDC1_HUMAN |
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