Human Proenkephalin-A/PENK Recombinant Protein (RPES2688)

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SKU:
RPES2688
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human Proenkephalin-A/PENK Recombinant Protein

Proenkephalin-A is a secreted protein that belongs to the opioid neuropeptide precursor family. Proenkephalin-A is an endogenous opioid polypeptide hormone which, via proteolyic cleavage, produces the enkephalin peptides [Met]enkephalin, and to a lesser extent, [Leu]enkephalin. Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Proenkephalin-A (114-133) and Proenkephalin-A (237-258) increase glutamate release in the striatum. Proenkephalin-A (114-133) decreases GABA concentration in the striatum.

Product Name:Human Proenkephalin-A/PENK Recombinant Protein (RPES2688)
Product Code:RPES2688
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Proenkephalin-A, Synenkephalin, Met-Enkephalin, Leu-Enkephalin, PENK
Accession:P01210
Sequence:Glu25-Phe267
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Proenkephalin-A is produced by our Mammalian expression system and the target gene encoding Glu25-Phe267 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:29.2 kDa
AP Mol Mass:36 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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