Human PI16 Recombinant Protein (RPPB2112)

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SKU:
RPPB2112
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
PI16
Synonyms:
Peptidase inhibitor 16
Synonyms:
PI-16
Synonyms:
Cysteine-rich secretory protein 9
Synonyms:
CRISP-9
Source:
HEK293 Cells
Uniprot:
Q6UXB8
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Description

Product Name:Human PI16 Recombinant Protein
Product Code:RPPB2112
Size:10µg
Species:Human
Target:PI16
Synonyms:Peptidase inhibitor 16, PI-16, Cysteine-rich secretory protein 9, CRISP-9, PSP94-binding protein, PI16, CRISP9, PSPBP, MSMBBP, MGC45378, DKFZp586B1817.
Source:HEK293 Cells
Physical Appearance:Filtered White lyophilized (freeze-dried) powder.
Formulation:PI16 was filtered (0.4µm) and lyophilized from 0.5mg/ml in 20mM Tris and 50mM NaCl, pH 7.5.
Solubility:It is recommended to add deionized water to prepare a working stock solution of 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Stability:Store lyophilized PI16 Human recombinant at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:LTDEEKRLMV ELHNLYRAQV SPPASDMLHM RWDEELAAFA KAYARQCVWG HNKERGRRGE NLFAITDEGM DVPLAMEEWH HEREHYNLSA ATCSPGQMCG HYTQVVWAKT ERIGCGSHFC EKLQGVEETN IELLVCNYEP PGNVKGKRPY QEGTPCSQCP SGYHCKNSLC EPIGSPEDAQ DLPYLVTEAP SFRATEASDS RKMGTPSSLA TGIPAFLVTE VSGSLATKAL PAVETQAPTS LATKDPPSMA TEAPPCVTTE VPSILAAHSL PSLDEEPVTF PKSTHVPIPK SADKVTDKTK VPSRSPENSL DPKMSLTGAR ELLPHAQEEA EAEAELPPSS EVLASVFPAQ DKPGELQATL DHTGHTSSKS LPNFPNTSAT ANATGGRALA LQSSLPGAEG PDKPSVVSGL NSGPGAAADY KDDDDK

Peptidase Inhibitor 16 (PI16) which a member of the CRISP family, is a putative serine protease inhibitor. PI16 interacts with PSP94/MSMB. PI16 is expressed in the prostate, testis, ovary and intestine. It also concentrates in prostate cancer patient's sera. PI16 may serve as a marker following prostatectomy for prostate cancer.

The Peptidase Inhibitor 16 Human Recombinant is produced in HEK293 cells and fused with a C-terminal Flag Tag (11 amino acids). The PI16 Flag Tagged Fusion Protein is 45.7kDa protein containing a total of 426 amino acid residues and purified by proprietary chromatographic techniques.

UniProt Protein Function:PI16: Putative serine protease inhibitor. Belongs to the CRISP family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 6p21.2
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q6UXB8
NCBI GenInfo Identifier:74749419
NCBI Gene ID:221476
NCBI Accession:Q6UXB8.1
UniProt Secondary Accession:Q6UXB8,Q6ZVG9, Q8IYL8, Q8NBK0, Q8TCB8
UniProt Related Accession:Q6UXB8
Molecular Weight:29,674 Da
NCBI Full Name:Peptidase inhibitor 16
NCBI Synonym Full Names:peptidase inhibitor 16
NCBI Official Symbol:PI16  
NCBI Official Synonym Symbols:CD364; PSPBP; CRISP9; MSMBBP  
NCBI Protein Information:peptidase inhibitor 16
UniProt Protein Name:Peptidase inhibitor 16
UniProt Synonym Protein Names:Cysteine-rich secretory protein 9; CRISP-9; PSP94-binding protein
Protein Family:Peptidase inhibitor
UniProt Gene Name:PI16  
UniProt Entry Name:PI16_HUMAN
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