Human PFKFB1 Recombinant Protein (RPES4328)

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SKU:
RPES4328
Product type:
Recombinant Protein
Host species:
Human Cells
Reactivity:
Human
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Description

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Human PFKFB1 Recombinant Protein

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

Product Name:Human PFKFB1 Recombinant Protein (RPES4328)
Product Code:RPES4328
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, 6PF-2-K/Fru-2,6-P2ase liver isozyme, Fructose-2,6-bisphosphatase, PFKFB1, F6PK, PFRX
Accession:P16118
Sequence:Ser2-Tyr471
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser2-Tyr471 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:55.6 kDa
AP Mol Mass:60 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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