Human PDCL3 Recombinant Protein (RPPB4214)

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SKU:
RPPB4214
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
PDCL3
Synonyms:
Phosducin-like protein 3
Synonyms:
VIAF1
Synonyms:
Viral IAP-associated factor 1
Synonyms:
HTPHLP
Source:
Escherichia Coli
Uniprot:
Q9H2J4
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Description

Product Name:Human PDCL3 Recombinant Protein
Product Code:RPPB4214
Size:20µg
Species:Human
Target:PDCL3
Synonyms:Phosducin-like protein 3, VIAF1, Viral IAP-associated factor 1, HTPHLP, VIAF-1, PHLP3, PHLP2A, IAP-associated factor VIAF1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The PDCL3 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMQDPNAD TEWNDILRKK GILPPKESLK ELEEEAEEEQ RILQQSVVKT YEDMTLEELE DHEDEFNEED ERAIEMYRRR RLAEWKATKL KNKFGEVLEI SGKDYVQEVT KAGEGLWVIL HLYKQGIPLC ALINQHLSGL ARKFPDVKFI KAISTTCIPN YPDRNLPTIF VYLEGDIKAQ FIGPLVFGGM NLTRDELEWK LSESGAIMTD LEENPKKPIE DVLLSSVRRS VLMKRDSDSE GD

PDCL3 belongs to the phosducin-like protein family which its members are known to bind to the beta-gamma subunits of G proteins. PDCL3 is a potential regulator of heterotrimeric G proteins and has a large amino acid sequence homology with phosducin.

PDCL3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 262 amino acids (1-239) and having a molecular mass of 30.0kDa.PDCL3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:PDCL3: Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. Belongs to the phosducin family.Protein type: ApoptosisChromosomal Location of Human Ortholog: 2q11.2Cellular Component: cytoplasm; nucleusMolecular Function: protein binding; queuine tRNA-ribosyltransferase activityBiological Process: positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; queuosine biosynthetic process; regulation of peptidyl-tyrosine phosphorylation
UniProt Protein Details:
NCBI Summary:This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]
UniProt Code:Q9H2J4
NCBI GenInfo Identifier:50401164
NCBI Gene ID:79031
NCBI Accession:Q9H2J4.1
UniProt Secondary Accession:Q9H2J4,Q53S68, B2RA00
UniProt Related Accession:Q9H2J4
Molecular Weight:27,614 Da
NCBI Full Name:Phosducin-like protein 3
NCBI Synonym Full Names:phosducin like 3
NCBI Official Symbol:PDCL3  
NCBI Official Synonym Symbols:VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A  
NCBI Protein Information:phosducin-like protein 3
UniProt Protein Name:Phosducin-like protein 3
UniProt Synonym Protein Names:HTPHLP; PhPL3; Viral IAP-associated factor 1; VIAF-1
Protein Family:Phosducin-like protein
UniProt Gene Name:PDCL3  
UniProt Entry Name:PDCL3_HUMAN
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