Human PCID2 Recombinant Protein (RPPB4197)

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SKU:
RPPB4197
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
PCID2
Synonyms:
PCI Domain Containing 2
Synonyms:
CSN12-Like Protein
Synonyms:
PCIDomain-Containing Protein 2
Synonyms:
F10
Source:
Escherichia Coli
Uniprot:
Q5JVF3
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Description

Product Name:Human PCID2 Recombinant Protein
Product Code:RPPB4197
Size:20µg
Species:Human
Target:PCID2
Synonyms:PCI Domain Containing 2, CSN12-Like Protein, PCIDomain-Containing Protein 2, F10, PCI domain-containing protein 2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:PCID2 protein solution (1.0 mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MAYKCQTVIV QSFLRAFQAH KEENWALPVM YAVALDLRVF ANNADQQLVK KGKSKVGDMLEKAAELLMSC FRVCASDTRA GIEDSKKWGM LFLVNQLFKI YFKINKLHLC KPLIRAIDSS NLKDDYSTAQRVTYKYYVGR KAMFDSDFKQ AEEYLSFAFEHCHRSSQKNK RMILIYLLPV KMLLGHMPTV ELLKKYHLMQ FAEVTRAVSEGNLLLLHEAL AKHEAFFIRC GIFLILEKLK IITYRNLFKK VYLLLKTHQL SLDAFLVALK FMQVEDVDIDEVQCILANLI YMGHVKGYIS HQHQKLVVSK QNPFPPLSTV C

PCIDomain Containing 2 (PCID2) is expressed in immature and early-stage Blymphocytes and regulates the expression of mitotic checkpoint protein MAD2. PCID2is a component of the TREX-2 complex, transcription and export complex 2, thiscomplex functions in docking export-competent ribonucleoprotein particles(mRNPs) to the nuclear entrance of the nuclear pore complex, nuclear basket.

PCID2 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 341 amino acids (80-399 a.a) andhaving a molecular mass of 39.3kDa.PCID2 is fused to a 21 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:This gene encodes a component of the TREX-2 complex (transcription and export complex 2), which regulates mRNA export from the nucleus. This protein regulates expression of Mad2 mitotic arrest deficient-like 1, a cell division checkpoint protein. This protein also interacts with and stabilizes Brca2 (breast cancer 2) protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
UniProt Code:Q5JVF3
NCBI GenInfo Identifier:16741617
NCBI Gene ID:55795
NCBI Accession:BC016614
UniProt Secondary Accession:Q5JVF3,Q3ZCX1, Q5TC57, Q5TC58, Q9H7K1, Q9HBZ7, Q9NUK6 Q9NVY1, Q9NW44, Q9NWH3
UniProt Related Accession:Q5JVF3
Molecular Weight:52,100 Da
NCBI Full Name:Homo sapiens PCI domain containing 2, mRNA
NCBI Synonym Full Names:PCI domain containing 2
NCBI Official Symbol:PCID2  
NCBI Official Synonym Symbols:F10  
NCBI Protein Information:PCI domain-containing protein 2
UniProt Protein Name:
UniProt Synonym Protein Names:
Protein Family:PCI domain-containing protein
UniProt Gene Name:
UniProt Entry Name:
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