Human NIP7 Recombinant Protein (RPPB4097)

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SKU:
RPPB4097
Product type:
Recombinant Protein
Size:
25ug
Species:
Human
Target:
NIP7
Synonyms:
Nuclear Import 7 Homolog
Synonyms:
60S ribosome subunit biogenesis protein NIP7 homolog KD93
Synonyms:
CGI-37
Synonyms:
HSPC031
Source:
Escherichia Coli
Uniprot:
Q9Y221
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Description

Product Name:Human NIP7 Recombinant Protein
Product Code:RPPB4097
Size:25µg
Species:Human
Target:NIP7
Synonyms:Nuclear Import 7 Homolog, 60S ribosome subunit biogenesis protein NIP7 homolog KD93, CGI-37, HSPC031, FLJ10296, NIP7.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The NIP7 protein solution contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MRPLTEEETR VMFEKIAKYI GENLQLLVDR PDGTYCFRLH NDRVYYVSEK IMKLAANISG DKLVSLGTCFGKFTKTHKFR LHVTALDYLA PYAKYKVWIK PGAEQSFLYG NHVLKSGLGR ITENTSQYQG VVVYSMADIPLGFGVAAKST QDCRKVDPMA IVVFHQADIG EYVRHEETLT LEHHHHHH

60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) belongs to NIP7 family and contains 1 PUA domain. NIP7 interacts with pre-ribosome complex and may bind to RNA. NIP7 is vital for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.

NIP7 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 188 amino acids (1-180 a.a.) and having a molecular mass of 21.5kDa.NIP7 is fused to 8 amino acids His Tag at C-terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:NIP7: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. Belongs to the NIP7 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Nucleolus; RNA-binding

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cytoplasm; nucleolus; nucleus

Molecular Function:protein binding

UniProt Code:Q9Y221
NCBI GenInfo Identifier:56404676
NCBI Gene ID:51388
NCBI Accession:Q9Y221.1
UniProt Secondary Accession:Q9Y221,Q9NZZ0, B2RD04,
UniProt Related Accession:Q9Y221
Molecular Weight:15,222 Da
NCBI Full Name:60S ribosome subunit biogenesis protein NIP7 homolog
NCBI Synonym Full Names:NIP7, nucleolar pre-rRNA processing protein
NCBI Official Symbol:NIP7  
NCBI Official Synonym Symbols:KD93; CGI-37; HSPC031  
NCBI Protein Information:60S ribosome subunit biogenesis protein NIP7 homolog
UniProt Protein Name:60S ribosome subunit biogenesis protein NIP7 homolog
UniProt Synonym Protein Names:KD93
Protein Family:60S ribosome subunit biogenesis protein
UniProt Gene Name:NIP7  
UniProt Entry Name:NIP7_HUMAN
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