Human MTHSFD Recombinant Protein (RPPB4018)

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SKU:
RPPB4018
Product type:
Recombinant Protein
Size:
20ug
Species:
Human
Target:
MTHSFD
Synonyms:
Methenyltetrahydrofolate synthase domain-containing protein
Synonyms:
Methenyltetrahydrofolate synthase domaincontaining protein
Synonyms:
Methenyltetrahydrofolate synthase
Source:
Escherichia Coli
Uniprot:
Q2M296
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Description

Product Name:Human MTHSFD Recombinant Protein
Product Code:RPPB4018
Size:20µg
Species:Human
Target:MTHSFD
Synonyms:Methenyltetrahydrofolate synthase domain-containing protein, Methenyltetrahydrofolate synthase domaincontaining protein, Methenyltetrahydrofolate synthase
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The MTHSFD solution (0.25mg/ml) contains 30% glycerol, 1mM DTT and Phosphate-Buffered Saline (pH 7.4).
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMEPRAVG VSKQDIREQI WGYMESQNLA DFPRPVHHRI PNFKGASHAA EQLPRLQAFK TARTIKVNPD APQKSARFFV LESKKTLLVP TPRLRTGLFN KITPPPGATK DILRKCATSQ GVRNYSVPIG LDSRVLVDLV VVGSVAVSEK GWRIGKGEGY ADLEYAMMVS MGAVSKETPV VTIVHDCQVV DIPEELVEEH DITVDYILTP TRVIATGCKR PKPMGITWFK ISLEMMEKIP ILRSLRAREQ QAGKDVTLQG EHQHLPEPGC QQTVPLSVGR RPPDTPGPET NSMEAAPGSP PGEGAPLAAD VYVGNLPGDA RVSDLKRALR ELGSVPLRLT WQGPRRRAFL HYPDSAAAQQ AVSCLQGLRL GTDTLRVALA RQQRDK

MTHSFD, also known as Methenyltetrahydrofolate Synthetase Domain Containing protein, is linked to Pancreas, Annular and Gastrointestinal Defects. It has also been associated with Immunodeficiency Syndrome. Some of the Gene Ontology annotations that are related to the MTHSFD gene are nucleic acid binding and nucleotide binding.

MTHSFD Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 406 amino acids (1-383 a.a.) and having a molecular mass of 44.5kDa. MTHSFD is fused to a 23 amino acid His tag at N-Terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:MTHFSD: 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:RNA-binding

Chromosomal Location of Human Ortholog: 16q24.1

UniProt Code:Q2M296
NCBI GenInfo Identifier:209572652
NCBI Gene ID:64779
NCBI Accession:Q2M296.2
UniProt Secondary Accession:Q2M296,Q9H878, Q9H954, A8MQ77, B7ZLC0, B7ZLC2, D3DUM9 E9PAM1,
UniProt Related Accession:Q2M296
Molecular Weight:41,996 Da
NCBI Full Name:Methenyltetrahydrofolate synthase domain-containing protein
NCBI Synonym Full Names:methenyltetrahydrofolate synthetase domain containing
NCBI Official Symbol:MTHFSD  
NCBI Protein Information:methenyltetrahydrofolate synthase domain-containing protein
UniProt Protein Name:Methenyltetrahydrofolate synthase domain-containing protein
Protein Family:Methenyltetrahydrofolate synthase domain-containing protein
UniProt Gene Name:MTHFSD  
UniProt Entry Name:MTHSD_HUMAN
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