Human MRTO4 Recombinant Protein (RPPB4000)

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SKU:
RPPB4000
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
MRTO4
Synonyms:
MRNA Turnover 4 Homolog (S Cerevisiae)
Synonyms:
MRT4 MRNA Turnover 4 Homolog (S Cerevisiae)
Synonyms:
60S Acidic Ribosomal Protein PO
Synonyms:
Chromosome 1 Open Reading Frame 33
Source:
Escherichia Coli
Uniprot:
Q9UKD2
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Description

Product Name:Human MRTO4 Recombinant Protein
Product Code:RPPB4000
Size:10µg
Species:Human
Target:MRTO4
Synonyms:MRNA Turnover 4 Homolog (S. Cerevisiae), MRT4 MRNA Turnover 4 Homolog (S. Cerevisiae), 60S Acidic Ribosomal Protein PO, Chromosome 1 Open Reading Frame 33, C1orf33, MRT4, DJ657E11.4.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The MRTO4 solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 1mM DTT and 20% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMPKSKRD KKVSLTKTAK KGLELKQNLI EELRKCVDTY KYLFIFSVAN MRNSKLKDIR NAWKHSRMFF GKNKVMMVAL GRSPSDEYKD NLHQVSKRLR GEVGLLFTNR TKEEVNEWFT KYTEMDYARA GNKAAFTVSL DPGPLEQFPH SMEPQLRQLG LPTALKRGVV TLLSDYEVCK EGDVLTPEQA RVLKLFGYEM AEFKVTIKYM WDSQSGRFQQ MGDDLPESAS ESTEESDSED DD

mRNA turnover protein 4 homolog (MRTO4) is a member of the ribosomal protein L10P family. MRTO4 is a protein sharing a low level of sequence similarity with ribosomal protein P0. Though the precise function of the MRTO4 is presently unknown, it seems to be involved in mRNA turnover and ribosome assembly. MRTO4 is a nucleolar component of the ribosome assembly apparatus which shares remarkable similarity and contends for binding to the 25S rRNA GAR domain with the ribosomal protein P0. The MRTO4 gene is located on human chromosome 1, which extends over 260 million base pairs, is comprised of over 3,000 genes and contains approximately 8% of the human genome.

MRTO4 Human Recombinant produced in E. coli is a single polypeptide chain containing 262 amino acids (1-239) and having a molecular mass of 29.9 kDa.MRTO4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:MRTO4: Involved in mRNA turnover and ribosome assembly. Belongs to the ribosomal protein L10P family.Protein type: Nucleolus; RNA-bindingChromosomal Location of Human Ortholog: 1p36.13Cellular Component: nuclear membrane; nucleolus; nucleoplasm; nucleusMolecular Function: protein binding; structural constituent of ribosomeBiological Process: ribosomal large subunit assembly and maintenance; rRNA processing
UniProt Protein Details:
NCBI Summary:This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq, Jul 2008]
UniProt Code:Q9UKD2
NCBI GenInfo Identifier:51316541
NCBI Gene ID:51154
NCBI Accession:Q9UKD2.2
UniProt Secondary Accession:Q9UKD2,Q5TG55, Q96SS6, Q9BPV9, B3KNB3
UniProt Related Accession:Q9UKD2
Molecular Weight:27,560 Da
NCBI Full Name:mRNA turnover protein 4 homolog
NCBI Synonym Full Names:MRT4 homolog, ribosome maturation factor
NCBI Official Symbol:MRTO4  
NCBI Official Synonym Symbols:MRT4; C1orf33; dJ657E11.4  
NCBI Protein Information:mRNA turnover protein 4 homolog
UniProt Protein Name:mRNA turnover protein 4 homolog
UniProt Synonym Protein Names:Ribosome assembly factor MRTO4
Protein Family:mRNA turnover protein
UniProt Gene Name:MRTO4  
UniProt Entry Name:MRT4_HUMAN
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