PE/Cyanine5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0673)

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SKU:
AGEL0673
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Applications:
FC
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The MIAP410-PE-Cyanine5 Conjugated Monoclonal Antibody (AGEL0673) provided by Assay Genie is a powerful tool for researchers studying CD47, a cell surface protein with key roles in immune regulation and cancer biology. This antibody is expertly designed to bind specifically to CD47 in human, mouse, and rat samples, enabling precise detection and analysis in a variety of experimental settings.CD47, also known as integrin-associated protein, is a multifunctional molecule involved in diverse cellular processes, including immune evasion and cell signaling. Its overexpression has been linked to cancer progression and metastasis, making it a promising target for anticancer therapies.

The MIAP410-PE-Cyanine5 Conjugated Monoclonal Antibody allows scientists to investigate the expression and function of CD47, advancing our understanding of its mechanisms and potential therapeutic applications.By utilizing this high-quality antibody, researchers can explore the intricate interactions of CD47 in immune responses, tumor microenvironment, and other biological processes. Whether investigating basic biology or developing novel treatment strategies, the MIAP410-PE-Cyanine5 Conjugated Monoclonal Antibody from Assay Genie is a valuable asset for cutting-edge research in immunology, oncology, and beyond.

Product Title:PE/Cyanine5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0673
Size:20 Tests, 100 Tests, 200 Tests
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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