Human MOB3B Recombinant Protein (RPPB2585)

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SKU:
RPPB2585
Product type:
Recombinant Protein
Size:
10ug
Species:
Human
Target:
MOB3B
Synonyms:
MOB Kinase Activator 3B
Synonyms:
Chromosome 9 Open Reading Frame 35
Synonyms:
Monopolar Spindle 1 Binding
Synonyms:
MOB1
Source:
Escherichia Coli
Uniprot:
Q86TA1
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Description

Product Name:Human MOB3B Recombinant Protein
Product Code:RPPB2585
Size:10µg
Species:Human
Target:MOB3B
Synonyms:MOB Kinase Activator 3B, Chromosome 9 Open Reading Frame 35, Monopolar Spindle 1 Binding, MOB1, Domain Containing, MOB1 Mps One Binder Kinase Activator-Like 2B, Mps One Binder Kinase Activator-Like 2B, Monopolar Spindle 1 Binding, Mob1 Homolog 2b, MOBKL2B, Domain Containing, C9orf35, MOB1D, MOB1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:The MOB3B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 20% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMSIALKQ VFNKDKTFRP KRKFEPGTQR FELHKRAQAS LNSGVDLKAA VQLPSGEDQN DWVAVHVVDF FNRINLIYGT ICEFCTERTC PVMSGGPKYE YRWQDDLKYK KPTALPAPQY MNLLMDWIEV QINNEEIFPT CVGVPFPKNF LQICKKILCR LFRVFVHVYI HHFDRVIVMG AEAHVNTCYK HFYYFVTEMN LIDRKELEPL KEMTSRMCH

MOB3B is similar to yeast Mob1 protein which binds Mps1p, a protein kinase vital for spindle pole body duplication and mitotic checkpoint regulation. MOB3B is situated on the opposite strand as the INF kappa precursor (IFNK) gene.

MOB3B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 239 amino acids (1-216) and having a molecular mass of 27.9 kDa. MOB3B is fused to a 23 amino acid His-tag at N-terminus.

UniProt Protein Function:MOBKL2B: May regulate the activity of kinases. Belongs to the MOB1/phocein family.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 9p21.2

Molecular Function:protein binding

NCBI Summary:The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q86TA1
NCBI GenInfo Identifier:56749334
NCBI Gene ID:79817
NCBI Accession:Q86TA1.2
UniProt Secondary Accession:Q86TA1,Q8NEB4, Q9H8V4,
UniProt Related Accession:Q86TA1
Molecular Weight:25,464 Da
NCBI Full Name:MOB kinase activator 3B
NCBI Synonym Full Names:MOB kinase activator 3B
NCBI Official Symbol:MOB3B  
NCBI Official Synonym Symbols:MOB1D; C9orf35; MOBKL2B  
NCBI Protein Information:MOB kinase activator 3B
UniProt Protein Name:MOB kinase activator 3B
UniProt Synonym Protein Names:Mob1 homolog 2b; Mps one binder kinase activator-like 2B
Protein Family:MOB kinase activator
UniProt Gene Name:MOB3B  
UniProt Entry Name:MOB3B_HUMAN
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